NSE gamma (Neuron Specific Enolase , gamma) (Neuroendocrine Marker) (ENO2/1375) , CF488A conjugate , 0.1mg / mL

This antibody recognizes a protein of about 50 kDa , which is identified as gamma-enolase. Three isoenzymes of enolases are identified , alpha , beta and gamma. Alpha-isoform is expressed in most tissues , whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers , and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins , such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin , Chromogranin A , and Neurofilament.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.