CD27(203.6) , Biotin conjugate , 0.1mg / mL

Recognizes a protein of a disulfide-linked 120 kDa dimer , identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells , medullary thymocytes , memory-type B cells , and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70 , a member of the TNF family , and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.