SOX9 / SRY-box 9(rSOX9/2288) , Biotin conjugate , 0.1mg / mL

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array , containing more than 19 , 000 , full-length human proteins. Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Nucleus (Potential). Campomelic dysplasia (CMD1) : Rare , often lethal , dominantly inherited , congenital osteo-chondrodysplasia , associated with male-to-female autosomal sex reversal in two-thirds of the affected karyotypic males. A disease of the newborn characterized by congenital bowing and angulation of long bones , unusually small scapulae , deformed pelvis and spine and a missing pair of ribs. Craniofacial defects such as cleft palate , micrognathia , flat face and hypertelorism are common. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.