YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)(rYBX1/2430) , Biotin conjugate , 0.1mg / mL

The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array , containing more than 19 , 000 full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus , YBX1 protein orchestrates transcription of proliferation-related genes , whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities , such as breast , lung and prostate cancer , cellular YBX1 expression indicates poor clinical outcome , suggesting that YBX1 is an attractive marker to predict patients' prognosis. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.