CD71 / Transferrin Receptor (TFRC) (Extracellular Domain)(TFRC/2898R) , Biotin conjugate , 0.1mg / mL

Recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71) , a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein , transferrin. This receptor is broadly distributed in carcinomas , sarcomas , leukemias , and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.