Interferon alpha-2 (IFNA2) (N27) , 1mg / mL

This antibody recognizes a protein of 16-27 kDa , identified as human interferon-alphaII (IFN-alphaII). Its epitope maps between aa43-53 of the IFN-alphaII) (total aa172). This MAb is specific for IFN-alpha(II) and does not cross-react with IFN-alpha(I). Epitopes of N27 and N39 MAb s are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-alpha(II) after viral infections. The IFN-alpha family consists of 24 or more genes or pseudo-genes. IFN-alphaII) is one of the two distinct families (I and II) of human IFN-alpha. The alpha interferons are mainly produced by lymphocytes , monocytes , macrophages , and cell lines such as Namalwa and KG1 following induction by viruses , nucleic acids , and glucocorticoid hormones. They are involved in virus resistance on target cells , inhibition of cell proliferation , induction of cytokines and regulation of expression of MHC class I antigens.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.