CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) (ITGAE/2474) , 1mg / mL

CD103 is alpha E integrin , belonging to a small beta-7 integrin subfamily. It is primarily expressed in intraepithelial lymphocytes. Together with beta 7 integrin , it is the cell surface receptor for E-cadherin , where it mediates cell adhesion. CD103 is expressed on more than 95% of intraepithelial CD8 cells and on 40% of mucosa-associated T cells , whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions , such as T-cell lymphomas and hairy cell leukemia (HCL) , the cells express CD103. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.