NFATc2IP rabbit pAb - 50 μL

Function: Plays a role in the inducible expression of Cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production. PTM: Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented Cytokine production. similarity: Contains 1 ubiquitin-like domain. subcellular location: TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. subunit: Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.