c-Myc(9E10.) , Biotin conjugate , 0.1mg / mL

The epitope of this antibody spans the Myc tag epitope , aa 410-419 (EQKLISEEDL) , which is a specific portion of an alpha helical region of human c-myc protein. Because the epitope is located at the dimerization site of the protein , the antibody is not sensitive for detecting endogenous c-myc , making it suitable for detecting Myc tagged proteins or myc overexpression. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease._x000D_ _x000D_ Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_