CD6 (Negative Marker of T-regulatory Cells) (C6/2884R) , Biotin conjugate , 0.1mg / mL

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence , three extracellular scavenger receptor cysteine-rich (SRCR) domains , a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 is present on mature thymocytes , peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.