FITC

Volume : 50 µg
Clone Number :
Aliases : ABBP 1 antibody; ABBP-1 antibody; ABBP1 antibody; Apobec 1 binding protein 1 antibody; APOBEC1 binding protein 1 antibody; APOBEC1-binding protein 1 antibody; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1- protein 1 antibody; FLJ40338 antibody; Heterogeneous nuclear ribonucleoprotein A/B antibody; hnRNP A/B antibody; hnRNP type A/B protein antibody; HNRNPAB antibody; HNRPAB antibody; ROAA_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99729
Immunogen : Recombinant Human Heterogeneous nuclear ribonucleoprotein A/B protein (1-68AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HNRNPAB
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Heterogeneous nuclear ribonucleoprotein A2 antibody; Heterogeneous nuclear ribonucleoprotein A2/B1 antibody; Heterogeneous nuclear ribonucleoprotein B1 antibody; Heterogeneous nuclear ribonucleoproteins A2/B1 antibody; hnRNP A2 / hnRNP B1 antibody; hnRNP A2 antibody; hnRNP A2/B1 antibody; hnRNP B1 antibody; hnRNP-A2 antibody; hnRNP-B1 antibody; hnRNPA2 antibody; Hnrnpa2b1 antibody; hnRNPB1 antibody; HNRPA2 antibody; HNRPA2B1 antibody; HNRPB1 antibody; Nuclear ribonucleoprotein particle A2 protein antibody; RNP A2 antibody; RNP B1 antibody; RNP-A2 antibody; RNP-B1 antibody; RNPA2 antibody; RNPB1 antibody; ROA2_HUMAN antibody; SNRPB1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P22626
Immunogen : Recombinant Human Heterogeneous nuclear ribonucleoproteins A2/B1 protein (1-249AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HNRNPA2B1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : HNRNPA 1 antibody; Helix destabilizing protein antibody; Helix-destabilizing protein antibody; Heterogeneous nuclear ribonucleoprotein A1 antibody; Heterogeneous nuclear ribonucleoprotein A1B protein antibody; Heterogeneous nuclear ribonucleoprotein B2 protein antibody; Heterogeneous nuclear ribonucleoprotein core protein A1 antibody; hnRNP A1 antibody; hnRNP core protein A1 antibody; HNRNPA1 antibody; HNRPA1 antibody; MGC102835 antibody; Nuclear ribonucleoprotein particle A1 protein antibody; ROA1_HUMAN antibody; Single strand DNA binding protein UP1 antibody; Single strand RNA binding protein antibody; Single-strand RNA-binding protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P09651
Immunogen : Recombinant Human Heterogeneous nuclear ribonucleoprotein A1 protein (2-354AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may mod µLate splice site selection. May play a role in HCV RNA replication.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HNRNPA1
Research Areas : Epigenetics and Nuclear Signaling; Microbiology

Volume : 50 µg
Clone Number :
Aliases : FLJ39654 antibody; FRTS4 antibody; Hepatic nuclear factor 4 alpha antibody; Hepatocyte nuclear factor 4 alpha antibody; Hepatocyte nuclear factor 4 antibody; Hepatocyte nuclear factor 4-alpha antibody; HNF 4 alpha antibody; HNF 4 antibody; HNF-4-alpha antibody; HNF4 antibody; HNF4A antibody; HNF4A_HUMAN antibody; HNF4a7 antibody; HNF4a8 antibody; HNF4a9 antibody; Hnf4alpha antibody; HNF4alpha10/11/12 antibody; MODY 1 antibody; MODY antibody; MODY1 antibody; NR2A1 antibody; NR2A21 antibody; Nuclear receptor subfamily 2 group A member 1 antibody; OTTHUMP00000031060 antibody; OTTHUMP00000031062 antibody; TCF 14 antibody; TCF antibody; TCF-14 antibody; TCF14 antibody; Tcf4 antibody; Transcription factor 14, hepatic nuclear factor antibody; Transcription factor 14 antibody; Transcription factor HNF 4 antibody; Transcription factor HNF-4 antibody; Transcription factor HNF4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P41235
Immunogen : Recombinant Human Hepatocyte nuclear factor 4-alpha protein (130-330AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HNF4A
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cardiovasc µLar; Developmental biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : HMX2 antibody; Homeobox protein HMX2 antibody; Homeobox protein H6 family member 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A2RU54
Immunogen : Recombinant Human Homeobox protein HMX2 protein (1-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMX2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

Volume : 50 µL
Clone Number :
Aliases : Heme oxygenase (decycling) 2 antibody; Heme oxygenase (decyclizing) 2 antibody; Heme oxygenase 2 antibody; HMOX 2 antibody; Hmox2 antibody; HMOX2 protein antibody; HMOX2_HUMAN antibody; HO 2 antibody; HO-2 antibody; HO2 antibody; OTTHUMP00000159847 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30519
Immunogen : Recombinant Human Heme oxygenase 2 protein (2-293AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 co µLd be implicated in the production of carbon monoxide in brain where it co µLd act as a neurotransmitter.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMOX2
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : 32 kD antibody; bK286B10 antibody; D8Wsu38e antibody; heat shock protein 32 kD antibody; heat shock protein 32kD antibody; Heat shock protein antibody; Heme oxygenase (decycling) 1 antibody; Heme oxygenase 1 antibody; Hemox antibody; HMOX 1 antibody; Hmox antibody; Hmox1 antibody; HMOX1_HUMAN antibody; HO 1 antibody; HO antibody; HO-1 antibody; HO1 antibody; Hsp32 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P09601
Immunogen : Recombinant Human Heme oxygenase 1 protein (3-288AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMOX1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD168 antibody; CD168 antigen antibody; HMMR antibody; HMMR_HUMAN antibody; Hyaluronan mediated motility receptor antibody; Hyaluronan-mediated motility receptor (RHAMM) antibody; IHABP antibody; Intracell µLar hyaluronic acid-binding protein antibody; MGC119494 antibody; MGC119495 antibody; OTTHUMP00000196920 antibody; Receptor for hyaluronan-mediated motility antibody; RHAMM antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75330
Immunogen : Recombinant Human Hyaluronan mediated motility receptor protein (478-653AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cell µLar transformation and metastasis formation, and in reg µLating extracell µLar-reg µLated kinase (ERK) activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMMR
Research Areas : Cancer; Developmental biology; Immunology; Stem cells

Volume : 50 µL
Clone Number :
Aliases : HMGXB4 antibody; HMG2L1 antibody; HMGBCG antibody; HMG domain-containing protein 4 antibody; HMG box-containing protein 4 antibody; High mobility group protein 2-like 1 antibody; Protein HMGBCG antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µgU5
Immunogen : Peptide sequence from Human HMG domain-containing protein 4 protein (489-509AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Negatively reg µLates Wnt/beta-catenin signaling during development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGXB4
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DKFZp686E20226 antibody; FLJ42187 antibody; High mobility group nucleosomal binding domain 3 antibody; High mobility group nucleosome-binding domain-containing protein 3 antibody; HMGN3 antibody; HMGN3_HUMAN antibody; OTTHUMP00000016772 antibody; OTTHUMP00000016773 antibody; PNAS 24 antibody; PNAS 25 antibody; PNAS24 antibody; PNAS25 antibody; Thyroid hormone receptor interacting protein 7 antibody; Thyroid receptor-interacting protein 7 antibody; TR-interacting protein 7 antibody; TRIP 7 antibody; TRIP-7 antibody; TRIP7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15651
Immunogen : Recombinant Human High mobility group nucleosome-binding domain-containing protein 3 protein (1-77AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds to nucleosomes, reg µLating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both ins µLin and glucagon levels and mod µLates the expression of pancreatic genes involved in ins µLin secretion. Reg µLates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Reg µLates the expression of SLC6A9, a glycine transporter which reg µLates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in oc µLar development and astrocyte function (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGN3
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial) antibody; 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 antibody; 3 hydroxy 3 methylglutaryl coenzyme A synthase antibody; 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody; HMCS2_HUMAN antibody; HMG CoA synthase antibody; HMG-CoA synthase antibody; HMGCS 2 antibody; HMGCS2 antibody; Hydroxymethylglutaryl CoA synthase antibody; Hydroxymethylglutaryl CoA synthase mitochondrial antibody; Hydroxymethylglutaryl-CoA synthase antibody; mitochondrial antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P54868
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA synthase, mitochondrial protein (426-508AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCS2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 3 hydroxy 3 methylglutaryl Coenzyme A synthase 1 (soluble) antibody; 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody; cytoplasmic antibody; EC 2.3.3.10 antibody; HMCS1_HUMAN antibody; HMG CoA synthase antibody; HMG-CoA synthase antibody; HMGCS antibody; HMGCS1 antibody; Hydroxymethylglutaryl CoA synthase, cytoplasmic antibody; Hydroxymethylglutaryl-CoA synthase antibody; MGC90332 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q01581
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA synthase, cytoplasmic protein (360-520AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCS1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 3 hydroxy 3 methylglutaryl CoA reductase antibody; 3 hydroxy 3 methylglutaryl Coenzyme A reductase antibody; 3 hydroxymethylglutaryl CoA reductase antibody; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody; 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody; 3H3M antibody; HMDH_HUMAN antibody; HMG CoA reductase antibody; HMG CoAR antibody; HMG-CoA reductase antibody; Hmgcr antibody; Hydroxymethylglutaryl CoA reductase antibody; LDLCQ3 antibody; MGC103269 antibody; Red antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04035
Immunogen : Recombinant Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein (588-887AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCR
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : HMGCLL1 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase antibody; cytoplasmic antibody; EC 4.1.3.4 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 antibody; Endoplasmic retic µLum 3-hydroxy-3-methylglutaryl-CoA lyase antibody; er-cHL antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TB92
Immunogen : Recombinant Human 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic protein (2-340AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCLL1
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase), HMGCL
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35914
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA lyase, mitochondrial protein (28-325aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as reg µLators of metabolism.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCL
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : HMGB4 antibody; High mobility group protein B4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WW32
Immunogen : Recombinant Human High mobility group protein B4 protein (1-186AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB4
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : chromosomal protein; Nonhistone; HMG4 antibody; High mobility group (nonhistone chromosomal) protein 4 antibody; High mobility group box 3 antibody; High mobility group protein 2a antibody; High mobility group protein 4 antibody; High mobility group protein B3 antibody; High mobility group protein HMG4 antibody; HMG 4 antibody; HMG-2a antibody; HMG-4 antibody; HMG2A antibody; HMGB 3 antibody; Hmgb3 antibody; HMGB3_HUMAN antibody; MGC90319 antibody; Non histone chromosomal protein antibody; Nonhistone chromosomal protein HMG4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15347
Immunogen : Recombinant Human High mobility group protein B3 protein (1-103AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively reg µLates B-cell and myeloid cell differentiation. In hematopoietic stem cells may reg µLate the balance between self-renewal and differentiation. Involved in negative reg µLation of canonical Wnt signaling (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : C80539 antibody; High mobility group (nonhistone chromosomal) protein 2 antibody; High mobility group box 2 antibody; High mobility group protein 2 antibody; High mobility group protein B2 antibody; HMG 2 antibody; HMG B2 antibody; HMG-2 antibody; HMG2 antibody; HMGB2 antibody; HMGB2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26583
Immunogen : Recombinant Human High mobility group protein B2 protein (43-185AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes. Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant reg µLatory sequences into close proximity (PubMed : 7797075, PubMed : 11909973, PubMed : 19522541 PubMed : 18413230, PubMed : 19965638, PubMed : 20123072). Involved in V(D)J recombination by acting as a cofactor of the RAG complex : acts by stim µLating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a promiscuous immunogenic DNA/RNA sensor which cooperates with subsequent discriminative sensing by specific pattern recognition receptors (By similarity). In the extracell µLar compartment acts as a chemokine. Promotes proliferation and migration of endothelial cells implicating AGER/RAGE (PubMed : 19811285). Has antimicrobial activity in gastrointestinal epithelial tissues (PubMed : 23877675). Involved in inflammatory response to antigenic stim µLus coupled with proinflammatory activity (By similarity). Involved in mod µLation of neurogenesis probably by reg µLation of neural stem proliferation (By similarity). Involved in artic µLar cartilage surface maintenance implicating LEF1 and the Wnt/beta-catenin pathway (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : High mobility group protein B1 (Amphoterin) (Heparin-binding protein p30) (High mobility group protein 1) (HMG-1), Hmgb1 Hmg-1 Hmg1
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P63159
Immunogen : Recombinant Rat High mobility group protein B1 protein (2-18aa)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications :
Background : M µLtifunctional redox sensitive protein with various roles in different cell µLar compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molec µLar pattern (DAMP) molec µLe that amplifies immune responses during tissue injury. Released to the extracell µLar environment can bind DNA, nucleosomes, IL-1 beta, CXCL12, AGER isoform 2/sRAGE, lipopolysaccharide (LPS) and lipoteichoic acid (LTA), and activates cells thro µgh engagement of m µLtiple surface receptors. In the extracell µLar compartment f µLly reduced HMGB1 (released by necrosis) acts as a chemokine, dis µLfide HMGB1 (actively secreted) as a cytokine, and s µLfonyl HMGB1 (released from apoptotic cells) promotes immunological tolerance (PubMed : 23519706, PubMed : 23446148, PubMed : 23994764, PubMed : 25048472). Has proangiogenic activity. May be involved in platelet activation. Binds to phosphatidylserine and phosphatidylethanolamide (PubMed : 11154118). Bound to RAGE mediates signaling for neuronal outgrowth (PubMed : 1885601 PubMed : 2461949, PubMed : 7592757, PubMed : 12183440). May play a role in accum µLation of expanded polyglutamine (polyQ) proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Hmgb1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : HEM3_HUMAN antibody; HMBS antibody; Hydroxymethylbilane synthase antibody; PBG D antibody; PBG-D antibody; PBGD antibody; PORC antibody; Porphobilinogen deaminase antibody; porphyria, acute, Chester type antibody; Pre uroporphyrinogen synthase antibody; Pre-uroporphyrinogen synthase antibody; UPS antibody; Uroporphyrinogen I synthase antibody; Uroporphyrinogen I synthetase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08397
Immunogen : Recombinant Human Porphobilinogen deaminase protein (283-330AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMBS
Research Areas : Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dJ324O17.1 antibody; H13 antibody; hIMP1 antibody; Histocompatibility (minor) 13 antibody; HM13 antibody; HM13_HUMAN antibody; IMP-1 antibody; IMP1 antibody; IMPAS antibody; IMPAS-1 antibody; Intramembrane protease 1 antibody; Intramembrane protease antibody; Minor histocompatibility antigen 13 antibody; Minor histocompatibility antigen H13 antibody; MSTP086 antibody; OTTHUMP00000030527 antibody; OTTHUMP00000030528 antibody; OTTHUMP00000030530 antibody; OTTHUMP00000214528 antibody; Presenilin-like protein 3 antibody; PSENL3 antibody; PSL3 antibody; Signal peptide peptidase antibody; Signal peptide peptidase beta antibody; SPP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TCT9
Immunogen : Recombinant Human Minor histocompatibility antigen H13 protein (336-377AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, res µLting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides (PubMed : 11714810). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein (PubMed : 12145199). Involved in the intramembrane cleavage of the integral membrane protein PSEN1 (PubMed : 12077416, PubMed : 11714810, PubMed : 14741365). Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed : 25239945). May play a role in graft rejection (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HM13
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : hly antibody; hla antibody; SAOUHSC_01121Alpha-hemolysin antibody; Alpha-HL antibody; Alpha-toxin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain NCTC 8325)
UniProt ID : Q2G1X0
Immunogen : Recombinant Staphylococcus aureus Alpha-hemolysin protein (27-319AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications :
Background : Alpha-toxin binds to the membrane of eukaryotic cells res µLting in the release of low-molec µLar weight molec µLes and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hly
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DNA-binding protein/plasminogen activator inhibitor 1 reg µLator antibody; Helicase like transcription factor antibody; Helicase-like transcription factor antibody; HIP116 antibody; HIP116A antibody; HLTF 1 antibody; Hltf antibody; HLTF_HUMAN antibody; HLTF1 antibody; p113 antibody; RING finger protein 80 antibody; RNF80 antibody; SMARC A3 antibody; SMARCA 3 antibody; SMARCA3 antibody; SNF2-like 3 antibody; SNF2L3 antibody; Sucrose nonfermenting protein 2 like 3 antibody; Sucrose nonfermenting protein 2-like 3 antibody; SWI/SNF related matrix associated actin dependent reg µLator of chromatin subfamily A member 3 antibody; SWI/SNF-related matrix-associated actin-dependent reg µLator of chromatin a3 antibody; SWI/SNF-related matrix-associated actin-dependent reg µLator of chromatin subfamily A member 3 antibody; ZBU 1 antibody; ZBU1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14527
Immunogen : Recombinant Human Helicase-like transcription factor protein (332-476AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability thro µgh acting as a ubiquitin ligase for \'Lys-63\'-linked polyubiquitination of chromatin-bound PCNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLTF
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : hlgC antibody; SAR2510 antibody; Gamma-hemolysin component C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain MRSA252)
UniProt ID : Q6GE13
Immunogen : Recombinant Staphylococcus aureus Gamma-hemolysin component C protein (30-315AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications :
Background : Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hlgC
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : hlgB antibody; SA2209 antibody; Gamma-hemolysin component B antibody; H-gamma-1 antibody; H-gamma-I antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain N315)
UniProt ID : P0A075
Immunogen : Recombinant Staphylococcus aureus Gamma-hemolysin component B protein (26-325AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications :
Background : Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hlgB
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Biotin [acetyl CoA carboxylase] ligase antibody; Biotin [methylcrotonoyl CoA carboxylase] ligase antibody; Biotin [methylmalonyl CoA carboxytransferase] ligase antibody; Biotin [propionyl CoA carboxylase [ATP hydrolyzing]] ligase antibody; Biotin apo protein ligase antibody; Biotin apo-protein ligase antibody; Biotin protein ligase antibody; Biotin--[acetyl-CoA-carboxylase] ligase antibody; BPL1_HUMAN antibody; HCS antibody; HLCS antibody; Holocarboxylase synthetase antibody; Holocarboxylase synthetase, EC 6.3.4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P50747
Immunogen : Recombinant Human Biotin--protein ligase protein (603-714AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLCS
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : B2 microglob µLin antibody; DADB-15K14.8 antibody; HLA 6.0 antibody; HLA class I histocompatibility antigen alpha chain G antibody; HLA class I histocompatibility antigen; alpha chain G antibody; HLA class I molec µLe antibody; HLA G antibody; HLA G antigen antibody; HLA G histocompatibility antigen class I G antibody; HLA G3 antibody; HLA-G antibody; HLA-G histocompatibility antigen; class I antibody; HLA60 antibody; HLAG antibody; HLAG_HUMAN antibody; Major histocompatibility complex class I G antibody; MHC class I antigen antibody; MHC class I antigen G antibody; MHC G antibody; T-cell A locus antibody; TCA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P17693
Immunogen : Recombinant Human HLA class I histocompatibility antigen, alpha chain G protein (25-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-G
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : CDA12 antibody; HLA 5.4 antibody; HLA class I histocompatibility antigen; alpha chain F antibody; HLA class I molec µLe antibody; HLA F antigen antibody; HLA-CDA12 antibody; HLA-F antibody; HLAF antibody; HLAF_HUMAN antibody; Leukocyte antigen F antibody; MHC class I antigen F antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30511
Immunogen : Recombinant Human HLA class I histocompatibility antigen, alpha chain F protein (194-303AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the presentation of foreign antigens to the immune system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-F
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA-E antibody; HLA-6.2 antibody; HLAEHLA class I histocompatibility antigen antibody; alpha chain E antibody; MHC class I antigen E) [Cleaved into : Soluble HLA class I histocompatibility antigen antibody; alpha chain E antibody; sHLA-E)] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13747
Immunogen : Recombinant Human HLA class I histocompatibility antigen, alpha chain E protein (33-261AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Non-classical major histocompatibility class Ib molec µLe involved in immune self-nonself discrimination. In complex with B2M/beta-2-microglob µLin binds nonamer self-peptides derived from the signal sequence of classical MHC class Ia molec µLes (VL9 peptides) (PubMed : 9754572, PubMed : 18083576, PubMed : 18339401). Peptide-bound HLA-E-B2M heterotrimeric complex primarily functions as a ligand for natural killer (NK) cell inhibitory receptor KLRD1-KLRC1 enabling NK cells to monitor the expression of other MHC class I molec µLes in healthy cells and to tolerate self (PubMed : 9754572, PubMed : 9486650, PubMed : 17179229, PubMed : 18083576). Upon cell µLar stress, preferentially binds signal sequence-derived peptides from stress-induced chaperones and is no longer recognized by NK cell inhibitory receptor KLRD1-KLRC1 res µLting in impaired protection from NK cells (PubMed : 12461076). Binds signal sequence-derived peptides from non-classical MHC class Ib HLA-G molec µLes and acts as a ligand for NK cell activating receptor KLRD1-KLRC2, likely playing a role in the generation and effector functions of adaptive NK cells and in maternal-fetal tolerance during pregnancy (PubMed : 9754572, PubMed : 30134159). Besides self-peptides, can also bind and present pathogen-derived peptides conformationally similar to VL9 peptides to alpha-beta T cell receptor (TCR) on unconventional CD8+ cytotoxic T cells, µLtimately triggering antimicrobial immune response (PubMed : 16474394, PubMed : 30087334).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-E
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : DR 4 antibody; DR beta 4 chain antibody; DR4 antibody; DRB1 transplantation antigen antibody; DRB4 antibody; DRB4_HUMAN antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen DR beta 4 chain antibody; HLA-DRB4 antibody; Human leucocyte antigen DRB4 antibody; Leukocyte antigen antibody; Major histocompatibility complex class II DR beta 4 antibody; MHC class II antigen DRB4 antibody; MHC class II antigen HLA DR beta antibody; MHC class2 antigen antibody; MHC HLA DR-beta chain antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13762
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DR beta 4 chain protein (30-227AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DRB4
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : DR beta 3 chain antibody; DR7 antibody; DRB3_HUMAN antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen DR beta 3 chain antibody; HLA class II histocompatibility antigen DRB1 7 beta chain antibody; HLA DR3B antibody; HLA-DRB3 antibody; Human leucocyte antigen DRB3 antibody; Major histocompatibility complex class II DR beta 3 antibody; MGC117330 antibody; MHC class II antigen DR beta 3 chain antibody; MHC class II antigen DRB3 antibody; MHC class II HLA DR beta 3 chain antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P79483
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DR beta 3 chain protein (111-227AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DRB3
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA class II histocompatibility antigen, DRB1-3 chain (Clone P2-beta-3) (MHC class II antigen DRB1*3), HLA-DRB1
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01912
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DRB1-3 chain protein (31-266AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes; and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments; exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides; autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs; other cells of the gastrointestinal tract; such as epithelial cells; express MHC class II molec µLes and CD74 and act as APCs; which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen; three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form an heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs; CD74 undergoes a sequential degradation by various proteases; including CTSS and CTSL; leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells; the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes; increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DRB1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DASS-397D15.1 antibody; DR alpha chain antibody; DR alpha chain precursor antibody; DRA_HUMAN antibody; DRB1 antibody; DRB4 antibody; FLJ51114 antibody; Histocompatibility antigen HLA DR alpha antibody; Histocompatibility antigen HLA-DR alpha antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen DR alpha chain antibody; HLA DR1B antibody; HLA DR3B antibody; HLA DRA antibody; HLA DRA1 antibody; HLA DRB1 antibody; HLA DRB3 antibody; HLA DRB4 antibody; HLA DRB5 antibody; HLA-DR histocompatibility type antibody; HLA-DRA antibody; HLADR4B antibody; HLADRA1 antibody; HLADRB antibody; Major histocompatibility complex class II DR alpha antibody; Major histocompatibility complex class II DR beta 1 antibody; Major histocompatibility complex class II DR beta 3 antibody; Major histocompatibility complex class II DR beta 4 antibody; Major histocompatibility complex class II DR beta 5 antibody; MGC117330 antibody; MHC cell surface glycoprotein antibody; MHC class II antigen DRA antibody; MHC II antibody; MLRW antibody; OTTHUMP00000029406 antibody; OTTHUMP00000029407 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01903
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DR alpha chain protein (28-254AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DRA
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : CELIAC1 antibody; DQ beta 1 chain antibody; DQB1_HUMAN antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen; DQ beta 1 chain antibody; HLA class II histocompatibility antigen; DQ beta 2 chain antibody; HLA DQB antibody; HLA DQB1 antibody; HLA-DQB1 antibody; HLA-DQB2 antibody; IDDM1 antibody; Lymphocyte antigen antibody; Major histocompatibility complex class II beta antibody; Major histocompatibility complex; class II; DQ beta 1 antibody; MHC class II antigen DQB1 antibody; MHC class II antigen HLA DQ beta 1 antibody; MHC class II DQ beta chain antibody; MHC class II HLA DQ beta glycoprotein antibody; MHC class2 antigen antibody; MHC DQ beta antibody; OTTHUMP00000029167 antibody; OTTHUMP00000178569 antibody; OTTHUMP00000178570 antibody; OTTHUMP00000178571 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01920
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DQ beta 1 chain protein (128-175AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DQB1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : DQ(6) alpha chain antibody; DQA2_HUMAN antibody; DX alpha antibody; DX alpha chain antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen DQ(6) alpha chain antibody; HLA class II histocompatibility antigen; DQ alpha 2 chain antibody; HLA DXA antibody; HLA-DQA1 antibody; HLA-DQA2 antibody; Major histocompatibility complex class II DQ alpha 2 antibody; MHC class II DQA2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01906
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DQ alpha 2 chain protein (24-214AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DQA2
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : CD antibody; CELIAC1 antibody; DC 1 alpha chain antibody; DC alpha antibody; DC-1 alpha chain antibody; DC-alpha antibody; DC1; included antibody; DQ alpha 1 chain antibody; DQ-A1 antibody; DQ-DRW9 alpha chain antibody; DQA1_HUMAN antibody; FLJ27088 antibody; FLJ27328 antibody; Gluten-sensitive enteropathy (celiac disease) antibody; GSE antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen; DQ alpha 1 chain antibody; HLA class II histocompatibility antigen; DQ(W3) alpha chain antibody; HLA-DCA antibody; HLA-DQA antibody; HLA-DQA1 antibody; HLA-DQA1 major histocompatibility complex; class II; DQ alpha 1 antibody; HLADC histocompatibility type antibody; Immune response antigens HIa; included antibody; leucocyte antigen DQA1 antibody; leukocyte antigen alpha chain antibody; LOC100133678 antibody; LOC100507686 antibody; LOC100509457 antibody; Major histocompatibility complex; class II; DQ alpha 1 antibody; MGC149527 antibody; MHC class II antigen antibody; MHC class II DQA1 antibody; MHC class II HLA-D alpha glycoprotein antibody; MHC class II HLA-DQ alpha 1 antibody; MHC class II surface glycoprotein antibody; MHC HLA-DQ alpha antibody; OTTHUMP00000029141 antibody; OTTHUMP00000176885 antibody; OTTHUMP00000178551 antibody; OTTHUMP00000178552 antibody; OTTHUMP00000233817 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01909
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DQ alpha 1 chain protein (24-213AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DQA1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : beta1 domain MHC class II HLA DPB antibody; class II histocompatibility antigen; DP(W4) beta chain antibody; class II HLA beta chain antibody; DP beta 1 chain antibody; DP(W4) beta chain antibody; DPB1 antibody; DPB1_HUMAN antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen; DP beta 1 chain antibody; HLA class II histocompatibility antigen; DP(W4) beta chain antibody; HLA DP14-beta chain antibody; HLA-DP antibody; HLA-DP histocompatibility type; beta-1 subunit antibody; HLA-DP1B antibody; HLA-DPB antibody; HLA-DPB1 antibody; major histocompatibility complex class II antigen beta chain antibody; major histocompatibility complex; class II; DP beta 1 antibody; MHC class II antigen beta chain antibody; MHC class II antigen DP beta 1 chain antibody; MHC class II antigen DPB1 antibody; MHC class II antigen DPbeta1 antibody; MHC class II HLA-DP-beta-1 antibody; MHC class II HLA-DRB1 antibody; MHC HLA DPB1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04440
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DP beta 1 chain protein (30-225AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DPB1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA-DPA1 antibody; HLA-DP1A antibody; HLASBHLA class II histocompatibility antigen antibody; DP alpha 1 chain antibody; DP(W3) antibody; DP(W4) antibody; HLA-SB alpha chain antibody; MHC class II DP3-alpha antibody; MHC class II DPA1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20036
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DP alpha 1 chain protein (29-222AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DPA1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA-DMA antibody; DMA antibody; RING6HLA class II histocompatibility antigen antibody; DM alpha chain antibody; MHC class II antigen DMA antibody; Really interesting new gene 6 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P28067
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DM alpha chain protein (27-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly syntheVolumed MHC class II molec µLes and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DMA
Research Areas : Cardiovasc µLar; Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA class I histocompatibility antigen, Cw-6 alpha chain (MHC class I antigen Cw*6), HLA-C, HLAC
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O78179
Immunogen : Recombinant Human HLA-C protein (25-308AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the presentation of foreign antigens to the immune system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-C
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : HLA class I histocompatibility antigen, B-14 alpha chain (MHC class I antigen B*14), HLA-B, HLAB
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96DW9
Immunogen : Recombinant Human HLA-B protein (25-308AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the presentation of foreign antigens to the immune system
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-B
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BC016235 antibody; Hexokinase domain containing 1 antibody; Hexokinase domain-containing protein 1 antibody; Hkdc1 antibody; HKDC1_HUMAN antibody; Putative hexokinase HKDC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q2TB90
Immunogen : Recombinant Human Putative hexokinase HKDC1 protein (129-427AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HKDC1
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DKFZp686M1669 antibody; Hexokinase 2 antibody; Hexokinase 2 muscle antibody; Hexokinase type II antibody; Hexokinase-2 antibody; HK 2 antibody; HK II antibody; HK2 antibody; HKII antibody; HxK 2 antibody; HxK2 antibody; HXK2_HUMAN antibody; Muscle form hexokinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52789
Immunogen : Recombinant Human Hexokinase-2 protein (334-526AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HK2
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BB404130 antibody; Brain form hexokinase antibody; dea antibody; DrHXK1 antibody; EC 2.7.1.1 antibody; Glycolytic enzyme antibody; HEXOKIN antibody; hexokinase I antibody; Hexokinase PI antibody; Hexokinase type I antibody; Hexokinase; tumor isozyme antibody; Hexokinase-1 antibody; Hexokinase-A antibody; HK I antibody; HK1 antibody; HK1 tb antibody; HK1 tc antibody; Hk1-s antibody; HK1-ta antibody; HK1-tb antibody; HK1-tc antibody; HKD antibody; HKI antibody; HMSNR antibody; HXK1 antibody; HXK1_HUMAN antibody; im : 7148527 antibody; mHk1-s antibody; wu : fc09d08 antibody; wu : fc16e02 antibody; wu : fc21e02 antibody; wu : fq14b11 antibody; zgc : 55790 antibody; zgc : 77618 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19367
Immunogen : Recombinant Human Hexokinase-1 protein (13-475AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HK1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : HJURP antibody; FAKTS antibody; FLEG1 antibody; URLC9 antibody; Holliday junction recognition protein antibody; 14-3-3-associated AKT substrate antibody; Fetal liver-expressing gene 1 protein antibody; Up-reg µLated in lung cancer 9 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NCD3
Immunogen : Recombinant Human Holliday junction recognition protein (1-748AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly syntheVolumed CENPA molec µLes into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HJURP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Histone H2B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Cairina moschata (Muscovy duck)
UniProt ID : P14001
Immunogen : Recombinant Crocodylus niloticus Histone H2B protein (2-93AA)
Raised in : Rabbit
Species Reactivity : Cairina moschata
Tested Applications :
Background : Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Histidine-rich protein PFHRP-II antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Plasmodium falciparum
UniProt ID : P05227
Immunogen : Recombinant Plasmodium falciparum Histidine-rich protein PFHRP-II protein (31-289AA)
Raised in : Rabbit
Species Reactivity : Plasmodium falciparum
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : HIST3H3 antibody; H3FT antibody; Histone H3.1t antibody; H3/t antibody; H3t antibody; H3/g antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16695
Immunogen : Recombinant Human Histone H3.1t protein (2-30AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HIST3H3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : HIST2H3A; antibody; HIST2H3C antibody; H3F2 antibody; H3FM; antibody; HIST2H3D antibody; Histone H3.2 antibody; Histone H3/m antibody; Histone H3/o antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q71DI3
Immunogen : Recombinant Human Histone H3.2 protein (108-136AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HIST2H3A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : hist2h2l antibody; zgc : 73093 antibody; Histone H2B 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Danio rerio (Zebrafish) (Brachydanio rerio)
UniProt ID : Q6PC60
Immunogen : Recombinant Zebrafish Histone H2B 3 protein (2-126AA)
Raised in : Rabbit
Species Reactivity : Zebrafish
Tested Applications :
Background : Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cell µLar machineries which require DNA as a template. Histones thereby play a central role in transcription reg µLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is reg µLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hist2h2l
Research Areas : Others