Volume : 50 µg
Clone Number :
Aliases : CD224 antibody; D22S672 antibody; D22S732 antibody; Gamma glutamyl transpeptidase antibody; Gamma glutamyltransferase 1 antibody; Gamma glutamyltranspeptidase 1 antibody; Gamma-glutamyltransferase 1 antibody; Gamma-glutamyltranspeptidase 1 light chain antibody; GGT 1 antibody; GGT antibody; GGT1 antibody; GGT1_HUMAN antibody; Glutamyl transpeptidase antibody; Glutathione hydrolase 1 antibody; GTG antibody; Leukotriene C4 hydrolase antibody; MGC96892 antibody; MGC96904 antibody; MGC96963 antibody; OTTHUMP00000028921 antibody; OTTHUMP00000197959 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19440
Immunogen : Recombinant Human Glutathione hydrolase 1 proenzyme protein (13-225AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cleaves the gamma-glutamyl bond of extracell µLar glutathione (gamma-Glu-Cys-Gly), glutathione conj µgates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracell µLar glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracell µLar GSH level. It is part of the cell antioxidant defense mechanism. Isoform 3 seems to be inactive.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : GGT1
Research Areas : Cancer; Metabolism; Signal transduction