EDEM1 rabbit pAb - 100 μL

Function: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. similarity: Belongs to the glycosyl hydrolase 47 family. subunit: Interacts with DERL2 and DERL3.