LY86 rabbit pAb - 50 μL

Function: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and Cytokine production. Important for efficient CD180 cell surface expression. induction: In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS). subcellular location: Associated with CD180 at the cell surface. subunit: Binds CD180. tissue specificity: Highly expressed in B-cells, monocytes and tonsil.