NEDL2 rabbit pAb - 50 μL

Function: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. pathway: Protein modification; protein ubiquitination. similarity: Contains 1 C2 domain. similarity: Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. similarity: Contains 2 WW domains. subunit: Interacts with TP73. tissue specificity: Predominantly expressed in adult brain, lung and heart.