NUT rabbit pAb - 100 μL

Disease: A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t (15;19) (q14;p13) with BRD4 which produces a BRD4-NUT fusion protein. Disease: A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t (15;9) (q14;q34) with BRD3 which produces a BRD3-NUT fusion protein. PTM: Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export. similarity: Belongs to the FAM22 family. subcellular location: Shuttles between nucleus and cytoplasm. tissue specificity: Specifically expressed in testis.