HRP labelled

Volume : 50 µg
Clone Number :
Aliases : Human intersectin SH3 domain containing protein SH3P17 antibody; Intersectin 1 SH3 domain protein antibody; intersectin 1 short form variant 3 antibody; intersectin 1 short form variant, 11 antibody; Intersectin short form antibody; intersectin short variant 12 antibody; Intersectin-1 antibody; Intersectin1 antibody; ITSN 1 antibody; ITSN antibody; itsn1 antibody; ITSN1_HUMAN antibody; MGC134948 antibody; MGC134949 antibody; OTTHUMP00000067855 antibody; OTTHUMP00000067856 antibody; OTTHUMP00000067857 antibody; OTTHUMP00000194810 antibody; OTTHUMP00000194811 antibody; OTTHUMP00000194812 antibody; OTTHUMP00000206688 antibody; SH3 domain containing protein 1A antibody; SH3 domain protein 1A antibody; SH3 domain-containing protein 1A antibody; SH3D1A antibody; SH3P17 antibody; Src homology 3 domain containing protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15811
Immunogen : Recombinant Human Intersectin-1 protein (773-916AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts as guanine nucleotide exchange factor (GEF) specific for the CDC42 GTPase (By similarity). Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May reg µLate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Isoform 1 co µLd be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITSN1
Research Areas : Neuroscience; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : ITPRIPL2 antibody; Inositol 14,5-trisphosphate receptor-interacting protein-like 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q3MIP1
Immunogen : Recombinant Human Inositol 14,5-trisphosphate receptor-interacting protein-like 2 protein (75-288AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITPRIPL2
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : Cleavage signal-1 protein antibody; CS-1 antibody; CS1 antibody; Ki-ras-induced actin-interacting protein antibody; KIAA1927 antibody; KRAP antibody; KRAS induced actin interacting protein antibody; SPAG13 antibody; Sperm associated antigen 13 antibody; Sperm-specific antigen 2 antibody; SSFA2 antibody; SSFA2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P28290
Immunogen : Recombinant Human Protein ITPRID2 protein (1-267AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITPRID2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : 4 antibody; 5-trisphosphate receptor antibody; 5-trisphosphate receptor type 1 antibody; DKFZp313E1334 antibody; DKFZp313N1434 antibody; inositol 1 4 5 triphosphate receptor type 1 antibody; Inositol 1 4 5 trisphosphate Receptor Type 1 antibody; Inositol 1 antibody; InsP3R1 antibody; IP3 antibody; IP3 receptor antibody; IP3 receptor isoform 1 antibody; IP3R 1 antibody; IP3R antibody; IP3R1 antibody; ITPR 1 antibody; Itpr1 antibody; ITPR1_HUMAN antibody; SCA15 antibody; SCA16 antibody; SCA29 antibody; Type 1 inositol 1 4 5 trisphosphate receptor antibody; Type 1 inositol 1 antibody; Type 1 InsP3 receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14643
Immunogen : Recombinant Human Inositol 14,5-trisphosphate receptor type 1 protein (1707-1966AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Intracell µLar channel that mediates calcium release from the endoplasmic retic µLum following stim µLation by inositol 14,5-trisphosphate (PubMed : 27108797). Involved in the reg µLation of epithelial secretion of electrolytes and fluid thro µgh the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITPR1
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ABRI antibody; ABri/ADan amyloid peptide antibody; BRI 2 antibody; BRI antibody; BRI2 antibody; BRICD 2B antibody; BRICD2B antibody; BRICHOS domain containing 2B antibody; E25B antibody; E3 16 antibody; E3-16 antibody; FBD antibody; imBRI2 antibody; Immature BRI2 antibody; Integral membrane protein 2B antibody; ITM 2B antibody; ITM2B antibody; ITM2B_HUMAN antibody; Protein E25B antibody; RDGCA antibody; Transmembrane protein BRI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y287
Immunogen : Recombinant Human Integral membrane protein 2B protein (81-148AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays a reg µLatory role in the processing of the beta-amyloid A4 precursor protein (APP) and acts as an inhibitor of the beta-amyloid peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITM2B
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : BRICD2A antibody; BRICHOS domain containing 2A antibody; E25 protein antibody; E25A antibody; Integral membrane protein 2A antibody; ITM2A antibody; ITM2A_HUMAN antibody; Protein E25 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43736
Immunogen : Recombinant Human Integral membrane protein 2A protein (79-263AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITM2A
Research Areas : Cell biology; Stem cells

Volume : 50 µg
Clone Number :
Aliases : ITIH5 antibody; KIAA1953 antibody; PP14776 antibody; UNQ311/PRO354 antibody; Inter-alpha-trypsin inhibitor heavy chain H5 antibody; ITI heavy chain H5 antibody; ITI-HC5 antibody; Inter-alpha-inhibitor heavy chain 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86UX2
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H5 protein (35-161AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a tumor suppressor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH5
Research Areas : Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 35 kDa inter-alpha-trypsin inhibitor heavy chain H4 antibody; gp120 antibody; H4P antibody; IHRP antibody; Inter-alpha-inhibitor heavy chain 4 antibody; Inter-alpha-trypsin inhibitor family heavy chain-related protein antibody; Inter-alpha-trypsin inhibitor heavy chain H4 antibody; inter-alpha-trypsin inhibitor, heavy chain-like, 1 antibody; ITI heavy chain H4 antibody; ITI-HC4 antibody; ITIH4 antibody; ITIH4_HUMAN antibody; ITIHL1 antibody; OTTHUMP00000197120 antibody; OTTHUMP00000197121 antibody; OTTHUMP00000213834 antibody; OTTHUMP00000213869 antibody; PK-120 antibody; PK120 antibody; Plasma kallikrein sensitive glycoprotein 120 antibody; PRO1851 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14624
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H4 protein (689-930AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH4
Research Areas : Cardiovasc µLar; Immunology

Volume : 50 µg
Clone Number :
Aliases : ITIH3 antibody; Inter-alpha-trypsin inhibitor heavy chain H3 antibody; ITI heavy chain H3 antibody; ITI-HC3 antibody; Inter-alpha-inhibitor heavy chain 3 antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q06033
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3 protein (512-651AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH3
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : H1P antibody; IATIH antibody; IGHEP1 antibody; Inter alpha (glob µLin) inhibitor H1 antibody; Inter alpha (glob µLin) inhibitor H1 polypeptide antibody; Inter alpha trypsin inhibitor heavy chain 1 antibody; Inter alpha trypsin inhibitor heavy chain H1 antibody; Inter-alpha-inhibitor heavy chain 1 antibody; Inter-alpha-trypsin inhibitor complex component III antibody; Inter-alpha-trypsin inhibitor heavy chain H1 antibody; ITI heavy chain H1 antibody; ITI-HC1 antibody; ITIH antibody; ITIH1 antibody; ITIH1_HUMAN antibody; Serum-derived hyaluronan-associated protein antibody; SHAP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19827
Immunogen : Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H1 protein (403-638AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to reg µLate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITIH1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Integrin beta-6 antibody; ITB6_HUMAN antibody; ITGB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18564
Immunogen : Recombinant Human Integrin beta-6 protein (451-586AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV : ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB6
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : FLJ26658 antibody; Integrin beta-5 antibody; Integrin subunit beta 5 antibody; integrin, beta 5 antibody; ITB5_HUMAN antibody; Itgb5 antibody; Testis secretory sperm-binding protein Li 217p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P18084
Immunogen : Recombinant Human Integrin beta-5 protein (431-637AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-V/beta-5 (ITGAV : ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD 104 antibody; CD104 antibody; CD104 antigen antibody; gp150 antibody; Integrin beta 4 subunit antibody; Integrin beta-4 antibody; ITB4_HUMAN antibody; ITG B4 antibody; ITGB 4 antibody; Itgb4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P16144
Immunogen : Recombinant Human Integrin beta-4 protein (1401-1533AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the reg µLation of keratinocyte polarity and motility. ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 95 subunit beta antibody; Beta 2 (antigen CD18 (p95) antibody; CD 18 antibody; CD18 antibody; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody; Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody; Complement component 3 receptor 3 and 4 subunit antibody; Complement receptor C3 beta subunit antibody; Complement receptor C3 subunit beta antibody; Integrin beta 2 antibody; Integrin beta chain beta 2 antibody; Integrin beta-2 (ITGB2) antibody; Integrin beta-2 antibody; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody; ITB2_HUMAN antibody; ITGB2 antibody; LAD antibody; LCAMB antibody; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody; Leukocyte cell adhesion molec µLe CD18 antibody; LFA 1 antibody; LFA1 antibody; Lymphocyte function associated antigen 1 (LFA1) antibody; Lymphocyte function associated antigen 1 antibody; MAC 1 antibody; MAC1 antibody; Macrophage antigen 1 (mac1) beta antibody; MF17 antibody; MFI7 antibody; OTTHUMP00000115278 antibody; OTTHUMP00000115279 antibody; OTTHUMP00000115280 antibody; OTTHUMP00000115281 antibody; OTTHUMP00000115282 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05107
Immunogen : Recombinant Human Integrin beta-2 protein (37-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed : 15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed : 11812992). Triggers neutrophil transmigration during lung injury thro µgh PTK2B/PYK2-mediated activation (PubMed : 18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed : 23775590).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB2
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKP3
Immunogen : Recombinant Human Integrin beta-1-binding protein 2 protein (130-329AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role during maturation and/or organization of muscles cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP2
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : ITGB1BP1 antibody; ICAP1Integrin beta-1-binding protein 1 antibody; Integrin cytoplasmic domain-associated protein 1 antibody; ICAP-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14713
Immunogen : Recombinant Human Integrin beta-1-binding protein 1 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key reg µLator of the integrin-mediated cell-matrix interaction signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha-5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. Plays a role in cell proliferation, differentiation, spreading, adhesion and migration in the context of mineralization and bone development and angiogenesis. Stim µLates cell µLar proliferation in a fibronectin-dependent manner. Involved in the reg µLation of beta-1 integrin-containing focal adhesion (FA) site dynamics by controlling its assembly rate during cell adhesion; inhibits beta-1 integrin clustering within FA by directly competing with talin TLN1 and hence stim µLates osteoblast spreading and migration in a fibronectin-and/or collagen-dependent manner. Acts as a guanine nucleotide dissociation inhibitor (GDI) by reg µLating Rho family GTPases during integrin-mediated cell matrix adhesion; reduces the level of active GTP-bound form of both CDC42 and RAC1 GTPases upon cell adhesion to fibronectin. Stim µLates the release of active CDC42 from the membranes to maintain it in an inactive cytoplasmic pool. Participates in the translocation of the Rho-associated protein kinase ROCK1 to membrane ruffles at cell leading edges of the cell membrane, leading to an increase of myoblast cell migration on laminin. Plays a role in bone mineralization at a late stage of osteoblast differentiation; mod µLates the dynamic formation of focal adhesions into fibrillar adhesions, which are adhesive structures responsible for fibronectin deposition and fibrillogenesis. Plays a role in blood vessel development; acts as a negative reg µLator of angiogenesis by attenuating endothelial cell proliferation and migration, lumen formation and sprouting angiogenesis by promoting AKT phosphorylation and inhibiting ERK1/2 phosphorylation thro µgh activation of the Notch signaling pathway. Promotes transcriptional activity of the MYC promoter.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGB1BP1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Itgb1 antibody; Integrin beta-1 antibody; Fibronectin receptor subunit beta antibody; VLA-4 subunit beta antibody; CD antigen CD29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P09055
Immunogen : Recombinant Mouse Integrin beta-1 protein (21-728AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Integrins alpha-1/beta-1 alpha-2/beta-1 alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1 alpha-3/beta-1 alpha-4/beta-1 alpha-5/beta-1 alpha-8/beta-1 alpha-10/beta-1 alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1 alpha-2/beta-1 alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1 cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stim µLation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, reg µLates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction thro µgh the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nod µLes. May be involved in up-reg µLation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1 serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successf µL completion of cytokinesis. ITGA4 : ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (By similarity). ITGA4 : ITGB1 and ITGA5 : ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Itgb1
Research Areas : Neuroscience; Developmental biology; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen identified by monoclonal antibody L230 antibody; CD 51 antibody; CD51 antibody; DKFZp686A08142 antibody; Integrin alpha five antibody; integrin alpha V beta 3 antibody; Integrin alpha-5 antibody; integrin alpha-V antibody; Integrin alpha-V light chain antibody; integrin alphaVbeta3 antibody; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody; ITAV_HUMAN antibody; ITGAV antibody; MSK 8 antibody; Msk8 antibody; Vitronectin receptor subunit alpha antibody; VNRA antibody; VTNR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06756
Immunogen : Recombinant Human Integrin alpha-V protein (775-885AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomod µLin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV : ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed : 23125415). ITGAV : ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGAV : ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed : 18441324). ITGAV : ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 19578119). ITGAV : ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGAV : ITGB3 and ITGAV : ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAV
Research Areas : Cancer; Cardiovasc µLar; Microbiology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : antigen CD11b (p170) antibody; Antigen CD11b p170 antibody; CD11 antigen like family member B antibody; CD11 antigen-like family member B antibody; CD11b antibody; CD11b/CD18 antibody; CD49d antibody; Cell surface glycoprotein MAC-1 subunit alpha antibody; Complement component 3 receptor 3 subunit antibody; Complement Component Receptor 3 Alpha antibody; Complement receptor type 3 antibody; Complement receptor type 3, alpha subunit antibody; CR 3 alpha chain (CR3A) antibody; CR 3 alpha chain antibody; CR-3 alpha chain antibody; CR3 antibody; CR3A antibody; F730045J24Rik antibody; Integrin Alpha M antibody; Integrin alpha M chain antibody; Integrin alpha-M antibody; Integrin beta 2 alpha subunit antibody; Integrin subunit alpha M antibody; integrin, alpha M (complement component 3 receptor 3 subunit) antibody; ITAM_HUMAN antibody; ITGAM antibody; Leukocyte adhesion receptor MO1 antibody; Ly-40 antibody; MAC 1 antibody; Mac-1a antibody; MAC1 antibody; Mac1 alpha subunit antibody; MAC1A antibody; Macrophage antigen alpha polypeptide antibody; MGC117044 antibody; Mo1 antibody; Mo1 alpha subunit antibody; MO1A antibody; Neutrophil adherence receptor alpha M subunit antibody; Neutrophil adherence receptor antibody; SLEB6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11215
Immunogen : Recombinant Human Integrin alpha-M protein (46-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and gran µLocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAM
Research Areas : Neuroscience; Tags & Cell Markers; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Antigen CD11A (p180); lymphocyte function associated antigen 1; alpha polypeptide antibody; CD11 antigen-like family member A antibody; CD11a antibody; CD18 antibody; CR3 antibody; Integrin alpha-L antibody; Integrin beta 2 antibody; Integrin gene promoter antibody; ITAL_HUMAN antibody; Itgal antibody; ITGAM antibody; ITGB2 antibody; LAD antibody; Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody; Leukocyte function-associated molec µLe 1 alpha chain antibody; LFA 1 alpha antibody; LFA 1 antibody; LFA-1A antibody; LFA1 antibody; LFA1A antibody; Lymphocyte function associated antigen 1 antibody; MAC1 antibody; MFI7 antibody; MO1A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20701
Immunogen : Recombinant Human Integrin alpha-L protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-L/beta-2 is a receptor for ICAM1 ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by gran µLocytes and monocytes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGAL
Research Areas : Immunology; Signal transduction; Stem cells

Volume : 50 µL
Clone Number :
Aliases : Integrin alpha 8 antibody; Integrin alpha-8 heavy chain antibody; Integrin alpha-8 light chain antibody; ITA8_HUMAN antibody; ITGA 8 antibody; ITGA8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53708
Immunogen : Peptide sequence from Human Integrin alpha-8 protein (114-131AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by reg µLating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1 SPP1 TGFB1 TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and reg µLates neurite outgrowth of sensory and motor neurons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA8
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : alpha 7 antibody; FLJ25220 antibody; Integrin alpha 7 antibody; Integrin alpha 7 chain antibody; Integrin alpha 7 heavy chain antibody; Integrin alpha 7 light chain antibody; Integrin alpha-7 70 kDa form antibody; ITA7_HUMAN antibody; ITGA 7 antibody; Itga7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13683
Immunogen : Recombinant Human Integrin alpha-7 protein (175-283AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and ad µLt myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vasc µLar smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA7
Research Areas : Cancer; Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Alpha6p antibody; CD49 antigen-like family member F antibody; CD49f antibody; Integrin alpha6B antibody; Integrin, alpha 6 antibody; ITA6_HUMAN antibody; ITGA6 antibody; ITGA6B antibody; Processed integrin alpha-6 antibody; VLA 6 antibody; VLA-6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P23229
Immunogen : Recombinant Human Integrin alpha-6 protein (625-866AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6 : ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed : 20682778). ITGA6 : ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed : 22351760).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA6
Research Areas : Developmental biology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : CD49 antigen-like family member E antibody; CD49e antibody; Fibronectin receptor subunit alpha antibody; Fibronectin receptor; alpha subunit antibody; FNRA antibody; Integrin alpha 5 (fibronectin receptor alpha) antibody; Integrin alpha-5 antibody; Integrin alpha-5 light chain antibody; Integrin alpha-F antibody; Integrin; alpha 5 (fibronectin receptor; alpha polypeptide) antibody; ITA5_HUMAN antibody; Itga5 antibody; Very late activation protein 5; alpha subunit antibody; VLA-5 antibody; VLA5 antibody; VLA5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08648
Immunogen : Recombinant Human Integrin alpha-5 protein (220-472AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5 : ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877). ITGA5 : ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed : 12807887, PubMed : 17158881).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA5
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : 269C wild type antibody; Antigen CD49D, alpha 4 subunit of VLA 4 receptor antibody; CD49 antigen like family member D antibody; CD49 antigen-like family member D antibody; CD49d antibody; IA4 antibody; Integrin alpha 4 antibody; Integrin alpha 4 subunit antibody; Integrin alpha IV antibody; Integrin alpha-4 antibody; Integrin alpha-IV antibody; Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA 4 receptor) antibody; ITA4_HUMAN antibody; ITGA4 antibody; MGC90518 antibody; OTTHUMP00000205320 antibody; Very late activation protein 4 receptor, alpha 4 subunit antibody; VLA 4 subunit alpha antibody; VLA-4 subunit alpha antibody; VLA4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13612
Immunogen : Recombinant Human Integrin alpha-4 protein (376-558AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. ITGA4 : ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed : 23125415). ITGA4 : ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed : 18635536, PubMed : 25398877).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA4
Research Areas : Cardiovasc µLar; Immunology; Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : AA407068 antibody; Antigen identified by monoclonal antibody J143 antibody; CD49 antigen like family member C antibody; CD49 antigen-like family member C antibody; CD49c antibody; CD49c antigen antibody; FLJ34631 antibody; FLJ34704 antibody; FRP 2 antibody; FRP-2 antibody; FRP2 antibody; Galactoprotein B3 antibody; GAP B3 antibody; GAPB3 antibody; Integrin alpha 3 antibody; Integrin alpha-3 light chain antibody; Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody; ITA3_HUMAN antibody; ITGA 3 antibody; Itga3 antibody; MSK18 antibody; VCA 2 antibody; VCA2 antibody; Very late activation protein 3 receptor alpha 3 subunit antibody; VL3A antibody; VLA 3 alpha chain antibody; VLA 3 subunit alpha antibody; VLA-3 subunit alpha antibody; VLA3a antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26006
Immunogen : Recombinant Human Integrin alpha-3 protein (168-276AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stim µLation by CSPG4 of endothelial cells migration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA3
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; GTA antibody; HPA3 antibody; Integrin alpha 2b antibody; Integrin alpha IIb antibody; Integrin alpha-IIb light chain antibody; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody; ITA2B_HUMAN antibody; Itga2b antibody; ITGAB antibody; platelet fibrinogen receptor, alpha subunit antibody; platelet glycoprotein IIb of IIb/IIIa complex antibody; Platelet membrane glycoprotein IIb antibody; platelet specific antigen BAK antibody; PPP1R93 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08514
Immunogen : Recombinant Human Integrin alpha-IIb protein (639-887AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction thro µgh binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically pl µgs ruptured endothelial cell surface.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA2B
Research Areas : Cardiovasc µLar; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BR antibody; CD 49b antibody; CD49 antigen like family member B antibody; CD49 antigen-like family member B antibody; CD49b antibody; CD49b antigen antibody; Collagen receptor antibody; DX5 antibody; Glycoprotein Ia deficiency included antibody; GP Ia antibody; GP Ia deficiency; included antibody; GPIa antibody; HPA 5 included antibody; HPA5 included antibody; Human platelet alloantigen system 5 antibody; Integrin alpha 2 antibody; Integrin alpha II antibody; Integrin alpha-2 antibody; Integrin; alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) antibody; ITA2_HUMAN antibody; ITGA2 antibody; Platelet alloantigen Br(a); included antibody; Platelet antigen Br antibody; Platelet glycoprotein GPIa antibody; Platelet glycoprotein Ia antibody; Platelet glycoprotein Ia/IIa antibody; Platelet membrane glycoprotein Ia antibody; Platelet receptor for collagen; deficiency of; included antibody; Very late activation protein 2 receptor alpha 2 subunit antibody; VLA 2 alpha chain antibody; VLA 2 antibody; VLA 2 subunit alpha antibody; VLA-2 subunit alpha antibody; VLA2 antibody; VLA2 receptor alpha 2 subunit antibody; VLAA2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P17301
Immunogen : Recombinant Human Integrin alpha-2 protein (188-365AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, mod µLation of collagen and collagenase gene expression, force generation and organization of newly syntheVolumed extracell µLar matrix.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA2
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CD 49a antibody; CD49 antigen-like family member A antibody; CD49a antibody; CD49a antigen antibody; Integrin alpha-1 antibody; ITA1_HUMAN antibody; Itga 1 antibody; ITGA1 antibody; Laminin and collagen receptor antibody; Very late activation protein 1 antibody; VLA 1 antibody; VLA-1 antibody; VLA1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P56199
Immunogen : Recombinant Human Integrin alpha-1 protein (242-524AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative reg µLation of EGF-stim µLated cell growth.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ITGA1
Research Areas : Signal transduction; Stem cells

Volume : 50 µg
Clone Number :
Aliases : DKFZp781N2395 antibody; Intestine-specific homeobox antibody; Isx antibody; ISX_HUMAN antibody; MGC138417 antibody; OTTHUMP00000028558 antibody; Pancreas intestine homeodomain transcription factor antibody; Pix 1 antibody; RAX like homeobox antibody; RAX-like homeobox antibody; RAXLX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q2M1V0
Immunogen : Recombinant Human Intestine-specific homeobox protein (1-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription factor that reg µLates gene expression in intestine. May participate in vitamin A metabolism most likely by reg µLating BCO1 expression in the intestine (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ISX
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : hIST1 antibody; Increased sodium tolerance 1 antibody; Increased sodium tolerance 1 homolog antibody; IST1 homolog antibody; IST1_HUMAN antibody; KIAA0174 antibody; MAPK activating protein PM28 antibody; MGC117220 antibody; MGC128433 antibody; Putative MAPK-activating protein PM28 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P53990
Immunogen : Recombinant Human IST1 homolog protein (172-284AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed : 19129479, PubMed : 19129480). During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex : IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtub µLe severing (PubMed : 26040712). Reg µLates early endosomal tub µLation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed : 23897888).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IST1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein antibody; Isoprenoid synthase domain-containing protein antibody; ispD antibody; ISPD_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A4D126
Immunogen : Recombinant Human Isoprenoid synthase domain-containing protein (1-264AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for protein O-linked mannosylation. Probably acts as a nucleotidyltransferase involved in synthesis of a nucleotide s µgar. Required for dystroglycan O-mannosylation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ISPD
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ISOC1 antibody; CGI-111 antibody; Isochorismatase domain-containing protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96CN7
Immunogen : Recombinant Human Isochorismatase domain-containing protein 1 protein (155-298AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : cytoplasm, extracell µLar exosome, peroxisome
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ISOC1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : isl1 antibody; isl-1 antibody; si : ch211-219f7.1 antibody; Ins µLin gene enhancer protein isl-1 antibody; Islet-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Danio rerio (Zebrafish) (Brachydanio rerio)
UniProt ID : P53405
Immunogen : Recombinant Zebrafish Ins µLin gene enhancer protein isl-1 protein (1-349AA)
Raised in : Rabbit
Species Reactivity : Zebrafish
Tested Applications : ELISA
Background : Binds to one of the cis-acting domain of the ins µLin gene enhancer. May be involved in subtype specialization of primary motoneurons.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : isl1
Research Areas : Neuroscience; Cardiovasc µLar; Developmental biology; Stem cells

Volume : 50 µg
Clone Number :
Aliases : G1P2 antibody; hUCRP antibody; IFI 15 antibody; IFI15 antibody; Interferon alpha inducible protein antibody; Interferon induced protein 15 antibody; Interferon induced protein IFI-15K antibody; Interferon stim µLated protein 15 kDa antibody; Interferon; alpha-inducible protein (clone IFI-15K) antibody; Interferon-induced 15 kDa protein antibody; Interferon-induced 17 kDa protein antibody; Interferon-induced 17-kDa/15-kDa protein antibody; IP17 antibody; ISG 15 antibody; ISG15 antibody; ISG15 ubiquitin like modifier antibody; ISG15_HUMAN antibody; Ubiquitin cross-reactive protein antibody; Ubiquitin-like protein ISG15 antibody; UCRP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05161
Immunogen : Recombinant Human Ubiquitin-like protein ISG15 protein (2-157AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Ubiquitin-like protein that is conj µgated to intracell µLar target proteins after IFN-alpha or IFN-beta stim µLation. Its enzymatic pathway is partially distinct from that of ubiquitin, differing in substrate specificity and interaction with ligating enzymes. ISG15 conj µgation pathway uses a dedicated E1 enzyme, but seems to converge with the Ub conj µgation pathway at the level of a specific E2 enzyme. Targets include STAT1 SERPINA3G/SPI2A, JAK1 MAPK3/ERK1 PLCG1 EIF2AK2/PKR, MX1/MxA, and RIG-1. Deconj µgated by USP18/UBP43. Shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors. May serve as a trans-acting binding factor directing the association of ligated target proteins to intermediate filaments. May also be involved in autocrine, paracrine and endocrine mechanisms, as in cell-to-cell signaling, possibly partly by inducing IFN-gamma secretion by monocytes and macrophages. Seems to display antiviral activity during viral infections. Ref.12 Ref.13 Ref.14 Ref.15 Ref.20 Ref.21In response to IFN-tau secreted by the conceptus, may ligate to and reg µLate proteins involved in the release of prostaglandin F2-alpha (PGF), and thus prevent lysis of the corpus luteum and maintain the pregnancy
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ISG15
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : 2310020H20Rik antibody; HML antibody; hnifU antibody; Iron s µLfur cluster assembly enzyme ISCU mitochondrial antibody; Iron s µLfur cluster scaffold homolog (E. coli) antibody; Iron s µLfur cluster scaffold homolog antibody; Iron-s µLfur cluster assembly enzyme ISCU antibody; Iscu antibody; IscU iron s µLfur cluster scaffold homolog antibody; ISCU_HUMAN antibody; ISU2 antibody; MGC74517 antibody; mitochondrial antibody; NIFU antibody; NifU like N terminal domain containing antibody; NifU like N terminal domain containing protein antibody; NifU like protein antibody; NifU-like N-terminal domain-containing protein antibody; NifU-like protein antibody; NIFUN antibody; Nitrogen fixation cluster like antibody; OTTHUMP00000238760 antibody; OTTHUMP00000238761 antibody; OTTHUMP00000238762 antibody; OTTHUMP00000238764 antibody; OTTHUMP00000238765 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H1K1
Immunogen : Recombinant Human Iron-s µLfur cluster assembly enzyme ISCU, mitochondrial protein (35-167AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the assembly or repair of the [Fe-S] clusters present in iron-s µLfur proteins. Binds iron.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ISCU
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : c14_5557 antibody; HESB like domain containing 1 antibody; HESB like domain containing protein 1 antibody; HESB-like domain-containing protein 1 antibody; iron s µLfur cluster assembly 2 homolog (S. cerevisiae) antibody; Iron s µLfur cluster assembly 2 homolog; mitochondrial antibody; Iron-s µLfur cluster assembly 2 homolog; mitochondrial antibody; ISCA2 antibody; ISCA2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86U28
Immunogen : Recombinant Human Iron-s µLfur cluster assembly 2 homolog, mitochondrial protein (9-154AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-s µLfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ISCA2
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : GK004 antibody; HESB-like domain-containing protein 2 antibody; hIscA antibody; Iron s µLfur assembly protein IscA antibody; Iron-s µLfur assembly protein IscA antibody; Iron-s µLfur cluster assembly 1 homolog antibody; Iron-s µLfur cluster assembly 1 homolog, mitochondrial antibody; ISCA1 antibody; ISCA1_HUMAN antibody; mitochondrial antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BUE6
Immunogen : Recombinant Human Iron-s µLfur cluster assembly 1 homolog, mitochondrial protein (67-122AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-s µLfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ISCA1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Homeodomain protein IRXB3 antibody; Iroquois class Homeodomain Protein 6 antibody; Iroquois class homeodomain protein IRX 6 antibody; Iroquois class homeodomain protein IRX6 antibody; Iroquois homeobox 6 antibody; Iroquois homeobox protein 1 like antibody; Iroquois homeobox protein 6 antibody; Iroquois homeobox protein 7 antibody; Iroquois-class homeodomain protein IRX-6 antibody; IRX 3 antibody; IRX 6 antibody; IRX3 antibody; Irx6 antibody; IRX6_HUMAN antibody; IRX7 antibody; IRXB3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P78412
Immunogen : Recombinant Human Iroquois-class homeodomain protein IRX-6 protein (289-389AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRX6
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Homeodomain protein IRXA3 antibody; Iroquois homeobox protein 4 antibody; Iroquois-class homeodomain protein IRX-4 antibody; Iroquoisclass homeodomain protein IRX4 antibody; Irx4 antibody; IRX4_HUMAN antibody; IRXA3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P78413
Immunogen : Recombinant Human Iroquois-class homeodomain protein IRX-4 protein (287-363AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Likely to be an important mediator of ventric µLar differentiation during cardiac development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRX4
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : AI894186 antibody; Homeodomain protein IRXB1 antibody; Iroquois class homeodomain protein IRX 1 antibody; Iroquois homeobox 3 antibody; Iroquois homeobox protein 3 antibody; Iroquois-class homeodomain protein irx-3 antibody; IRX 1 antibody; irx3 antibody; IRX3_HUMAN antibody; IRXB1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P78415
Immunogen : Recombinant Human Iroquois-class homeodomain protein IRX-3 protein (285-378AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRX3
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : Ins µLin receptor substrate 2 antibody; IRS 2 antibody; IRS-2 antibody; Irs2 antibody; IRS2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y4H2
Immunogen : Recombinant Human Ins µLin receptor substrate 2 protein (766-1001AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May mediate the control of various cell µLar processes by ins µLin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRS2
Research Areas : Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : IFN alpha responsive transcription factor subunit antibody; IFN-alpha-responsive transcription factor subunit antibody; Interferon reg µLatory factor 9 antibody; interferon stim µLated transcription factor 3 antibody; Interferon-stim µLated gene factor 3 gamma antibody; interferon-stim µLated transcription factor 3, gamma 48kDa antibody; IRF 9 antibody; IRF-9 antibody; Irf9 antibody; IRF9_HUMAN antibody; ISGF 3 gamma antibody; ISGF-3 gamma antibody; ISGF3 antibody; ISGF3 p48 subunit antibody; ISGF3G antibody; OTTHUMP00000164692 antibody; OTTHUMP00000164693 antibody; p48 antibody; Transcriptional reg µLator ISGF3 subunit gamma antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00978
Immunogen : Recombinant Human Interferon reg µLatory factor 9 protein (44-180AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1 : STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stim µLated response element (ISRE) to activate the transcription of interferon stim µLated genes, which drive the cell in an antiviral state.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRF9
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : Irf8 antibody; Icsbp antibody; Icsbp1 antibody; Interferon reg µLatory factor 8 antibody; IRF-8 antibody; Interferon consensus sequence-binding protein antibody; ICSBP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P23611
Immunogen : Recombinant Mouse Interferon reg µLatory factor 8 protein (1-424AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Specifically binds to the upstream reg µLatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a reg µLatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5\'-TGAnTCA/GAAA-3\'), an immune-specific reg µLatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Irf8
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : IMD39 antibody; Interferon reg µLatory factor 7 antibody; Interferon reg µLatory factor 7H antibody; IRF 7 antibody; IRF 7A antibody; IRF 7H antibody; IRF-7 antibody; IRF7 antibody; IRF7_HUMAN antibody; IRF7A antibody; IRF7B antibody; IRF7C antibody; IRF7H antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92985
Immunogen : Recombinant Human Interferon reg µLatory factor 7 protein (131-289AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key transcriptional reg µLator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Reg µLates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stim µLated genes (ISG) by binding to an interferon-stim µLated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase. Exists in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization where along with other coactivators it can activate transcription of the type I IFN and ISG genes. Can also play a role in reg µLating adaptive immune responses by inducing PSMB9/LMP2 expression, either directly or thro µgh induction of IRF1. Binds to the Q promoter (Qp) of EBV nuclear antigen 1 a (EBNA1) and may play a role in the reg µLation of EBV latency. Can activate distinct gene expression programs in macrophages and reg µLate the anti-tumor properties of primary macrophages.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRF7
Research Areas : Epigenetics and Nuclear Signaling; Immunology; Microbiology

Volume : 50 µg
Clone Number :
Aliases : Interferon reg µLatory factor 6 antibody; IRF 6 antibody; IRF-6 antibody; IRF6 antibody; IRF6_HUMAN antibody; LPS antibody; OFC 6 antibody; OFC6 antibody; OTTHUMP00000034677 antibody; OTTHUMP00000034678 antibody; PIT antibody; PPS antibody; PPS1 antibody; VWS antibody; VWS1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14896
Immunogen : Recombinant Human Interferon reg µLatory factor 6 protein (43-285AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in reg µLating mammary epithelial cell proliferation (By similarity). May reg µLate WDR65 transcription (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRF6
Research Areas : Epigenetics and Nuclear Signaling; Immunology; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Interferon reg µLatory factor 5 antibody; Interferon reg µLatory factor 5 bone marrow variant antibody; IRF 5 antibody; IRF-5 antibody; Irf5 antibody; IRF5_HUMAN antibody; SLEB10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13568
Immunogen : Recombinant Human Interferon reg µLatory factor 5 protein (214-395AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRF5
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : IRF3 protein (Interferon reg µLatory factor 3, isoform CRA_b), IRF3
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96GL3
Immunogen : Recombinant Human IRF3 protein (1-452AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRF3
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : DKFZp434M154 antibody; I2BP1_HUMAN antibody; Interferon reg µLatory factor 2 binding protein 1 antibody; Interferon reg µLatory factor 2-binding protein 1 antibody; IRF 2BP1 antibody; IRF-2-binding protein 1 antibody; IRF-2BP1 antibody; IRF2 binding protein 1 antibody; Irf2bp1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IU81
Immunogen : Recombinant Human Interferon reg µLatory factor 2-binding protein 1 protein (340-499AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IRF2BP1
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : ACO3 antibody; FLJ23381 antibody; IRE BP2 antibody; IRE-BP 2 antibody; IREB 2 antibody; IREB2 antibody; IREB2_HUMAN antibody; Iron reg µLatory protein 2 antibody; iron responsive element binding protein 2 antibody; Iron-responsive element-binding protein 2 antibody; IRP 2 antibody; IRP2 antibody; IRP2AD antibody; OTTHUMP00000185022 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P48200
Immunogen : Recombinant Human Iron-responsive element-binding protein 2 protein (107-216AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5\'-UTR of ferritin, and delta aminolev µLinic acid synthase mRNAs, and in the 3\'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin res µLts in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : IREB2
Research Areas : Cardiovasc µLar; Metabolism