Cytokeratin , LMW(AE-1) , Biotin conjugate , 0.1mg / mL

This MAb recognizes the 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5 , 55 , 51 , 50 , 50' , 48 , 46 , 45 , and 40 kDa. MAb AE3 recognizes the 65-67 , 64 , 59 , 58 , 56 , and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail , which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung , liver carcinoma , breast cancer , and esophageal cancer.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.