CD3e(RIV9) , Biotin conjugate , 0.1mg / mL

Reacts with five invariable CD3 chains designated CD3y , CD3d , CD3e , CD3f , and CD3n with molecular weight ranging from 16-28 kDa.  CD3 , also known as T3 , is a member of the immunoglobulin superfamily that plays a role in antigen recognition , signal transduction , and T cell activation. It is found on all mature T-lymphocytes , NK , T-cells , and some thymocytes. It is expressed , typically at high levels , on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and , in cortical thymus , CD3 is predominantly intracytoplasmic. This MAb is particularly useful for induction of T cell activation in vitro and in vivo due to its unusual IgG3 isotype._x000D_ _x000D_ Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_