HLA-Aw32 & HLA-A25 (MHC I)(CATA-1) , Biotin conjugate , 0.1mg / mL

This MAb reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition , a reaction was observed with a cell of phenotype A2 , Aw31; B17 , Bw49. HLA-A , with HLA-B and HLA-C , belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor , inhibition of NK cell cytotoxicity , and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This MAb is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.