PGP9.5 / UchL1 (pan-Neuronal Marker) (rUCHL1/775) , Biotin conjugate , 0.1mg / mL

This MAb reacts with a protein of 20-30 kDa , identified as PGP9.5 , also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially , PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium , spermatogonia , Leydig cells , oocytes , melanocytes , prostatic secretory epithelium , ejaculatory duct cells , epididymis , mammary epithelial cells , Merkel cells , and dermal fibroblasts. Furthermore , immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease._x000D_ _x000D_ Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_