NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker)(rNGFR/1965) , Biotin conjugate , 0.1mg / mL

Recognizes a glycoprotein of 75 kDa , identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes , melanomas , neuroblastomas , pheochromocytomas and neurofibromas. Reportedly , anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells , dental pulp cells , lymphoidal follicular dendritic cells , basal epithelium of oral mucosa and hair follicles , prostate basal cells , and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.