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CD54  /  ICAM-1(15.2) ,   Biotin  conjugate ,   0.1mg / mL

CD54 / ICAM-1(15.2) , Biotin conjugate , 0.1mg / mL

https://www.glycotech.com/web/image/product.template/197860/image_1920?unique=2421920
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Recognizes an 85-115 kDa protein (variation with cell type) , identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family , present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts , EC , macrophages , and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule , LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

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Internal Reference: BNCB2853-500
Website URL: /shop/bncb2853-500-cd54-icam-1-15-2-biotin-conjugate-0-1mg-ml-197860