CLEC9A / DNGR1 (Dendritic Cell Marker)(8F9) , Biotin conjugate , 0.1mg / mL

This MAb recognizes a protein of 27 kDa , identified as CLEC9A (C-type lectin domain family 9 member A). Its epitopes maps in aa 50-110. The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions , including cell-cell signaling , cell adhesion , glycoprotein turnover and immune responses. CLEC-9A , also known as DNGR1 (dendritic cell natural killer lectin group receptor 1) , is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells , brain , spleen and thymus , CLEC-9A is a group V C-type lectin- like receptor (CTLR) that acts as an activation receptor. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.