FOLH1 / PSMA (Prostate Epithelial Marker)(FOLH1/3149R) , Biotin conjugate , 0.1mg / mL

Folate hydrolase 1 (FOLH1) , also known as Prostate-specific membrane antigen (PSMA) , is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities , one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.