Retinol Binding Protein-1 (RBP1)(rRBP1/872) , Biotin conjugate , 0.1mg / mL

This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1) , a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins , which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues , like the eye , where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation , where it binds further to the protein transthyretin , to form a transporting complex , which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary , pancreas , pituitary gland , adrenal gland , and fetal liver. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.