TDP-25 Aggregation Assay Cell Line

Description A novel fluorescence cell-based assay cell line was developed for High Content Screening that allows the quantification of pathological TDP-25 aggregates. TDP-25 Aggregation Assay Cell Line consists in a U2OS cell line stably expressing the 25-kDa C-terminal fragment of TDP-43 (a.k.a. TDP-25). This cell line is offered as a “stable cell line” in cryopreserved vials. Each vial of U2OS cell line stably expressing fluorescent TDP-25 contains 3 million cells. We provide 2 vials of cells with each order. These cells proliferate in vitro and they are guaranteed to further expand for more than 30 passages following the instructions provided in the technical sheet. 2 vials, 3 x 10^6 cells/ vial