Rab 5A rabbit pAb - 50 μL

Enzyme regulation: Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. function: Required for the fusion of plasma membranes and early endosomes. similarity: Belongs to the small GTPase superfamily. Rab family. subcellular location: Enriched in stage I melanosomes. subunit: Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, UNC84B, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3.