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ABHD4 rabbit pAb - 100 μL

ABHD4 rabbit pAb - 100 μL

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Caution: Thr-291 is present instead of the conserved His which is expected to be an active site residue. function: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. similarity: Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.

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Internal Reference: ES7138
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ABHD4 rabbit pAb
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