p55;50 EBV-Early Antigen(1108-1) , Biotin conjugate , 0.1mg / mL

Epstein-Barr virus (EBV) , also designated human herpesvirus 4 (HHV-4) , is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and , though often asymptomatic , it can cause infectious mononucleosis , a disease characterized by fatigue , fever , sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1 , the gene that encodes for Ea-D , is closely associated with the gene encoding for EBV DNA polymerase , and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and , together , they may play a role in viral replication._x000D__x000D_Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.