Cdk2 / p34cdc2 Serine-Threonine Kinase(AN4.3) , Biotin conjugate , 0.1mg / mL

In vertebrates , as in yeast , multiple cyclins have been identified , including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast , the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells , a second Cdc2-related kinase has also been implicated in cell cycle control. This protein , designated cyclindependent kinase 2 (Cdk2) , also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2-related cyclin dependent kinases have been identified. These include Cdk3 , Cdk4 , Cdk5 , PCTAIRE-1 , PCTAIRE-2 , PCTAIRE-3 , Cdk6 Cdk7 , Cdk8 and KKIALRE. Primary antibodies are available purified , or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets , because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.