c-Jun (Phospho Ser249) rabbit pAb - 50 μL

Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. PTM: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC. similarity: Belongs to the bZIP family. similarity: Belongs to the bZIP family. Jun subfamily. similarity: Contains 1 bZIP domain. subunit: Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.