Volume : 50 µg
Clone Number :
Aliases : C76981 antibody; Dentin matrix protein 4 antibody; DKFZp547C074 antibody; DMP-4 antibody; DMP4 antibody; DMP4_HUMAN antibody; Extracell µLar serine/threonine protein kinase Fam20C antibody; Fam20c antibody; Family with sequence similarity 20 member C antibody; GEF CK antibody; Golgi enriched fraction casein kinase antibody; Protein FAM20C antibody; RNS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IXL6
Immunogen : Recombinant Human Extracell µLar serine/threonine protein kinase FAM20C protein (107-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed : 22582013, PubMed : 23754375, PubMed : 25789606). Constitutes the main protein kinase for extracell µLar proteins, generating the majority of the extracell µLar phosphoproteome (PubMed : 26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed : 26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed : 22582013, PubMed : 25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed : 26091039).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FAM20C
Research Areas : Developmental biology; Signal transduction; Stem cells