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Complex Carbohydrates

Multivalent Biotinylated Polymers

Univalent Biotinylated Probes

Multivalent Fluoresceinated Polymers

Multivalent Polymers and Sets

Sets of Carbohydrate Polymers

Glycoamino Acids

Sialic Acid Derivatives

Muramyl Peptides

Acetylated Saccharides

Anti-Carbohydrate

Anti-E-Selectin

Parallel Plate Flow Chambers

Wash Chamber for Static Cell Adhesion

Chamber for Cell Adhesion on TLC Plates

Supporting Product

FITC

Conjugated antibodies for Flow Cytometry of Facs instruments BD FACS Calibur: Equipped with a 488 nm blue laser, suitable for FITC excitation.

BD LSR II: Configurable with up to four lasers, including a 488 nm blue laser for FITC detection.
 
BD FACS Canto II: Features a 488 nm blue laser, optimized for FITC detection with a sensitivity of <100 MESF.
  

BD LSR Fortessa: High-end analyzer configurable with multiple lasers, including a 488 nm blue laser for FITC detection.

BD FACS Symphony A5: Advanced analyzer with customizable laser configurations, supporting FITC detection.

BD FACS Melody: User-friendly cell sorter with a 488 nm blue laser, suitable for FITC-labeled samples.
CDKN2AIPNL Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C2AIL antibody; C2AIL_HUMAN antibody; CDKN2A interacting protein N terminal like antibody; CDKN2A interacting protein N terminal like protein antibody; CDKN2A-interacting protein N-terminal-like protein antibody; CDKN2AIP N terminal like protein antibody; CDKN2AIP N-terminal-like protein antibody; Cdkn2aipnl antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96HQ2
Immunogen : Recombinant Human CDKN2AIP N-terminal-like protein (1-116AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDKN2AIPNL
Research Areas : Cell biology
0.01 € 0.01 EUR
CDKN2A Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDKN2A antibody; CDKN2 antibody; MTS1 antibody; Cyclin-dependent kinase inhibitor 2A antibody; Cyclin-dependent kinase 4 inhibitor A antibody; CDK4I antibody; M µLtiple tumor suppressor 1 antibody; MTS-1 antibody; p16-INK4a antibody; p16-INK4 antibody; p16INK4A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P42771
Immunogen : Recombinant Human Cyclin-dependent kinase inhibitor 2A protein (1-86AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Acts as a negative reg µLator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDKN2A
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDKN1C Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Beckwith Wiedemann syndrome antibody; BWCR antibody; BWS antibody; CDKI antibody; CDKN 1C antibody; CDKN1C antibody; CDN1C_HUMAN antibody; Cyclin dependent kinase inhibitor 1C antibody; Cyclin dependent kinase inhibitor p57 antibody; Cyclin-dependent kinase inhibitor 1C antibody; Cyclin-dependent kinase inhibitor p57 antibody; KIP 2 antibody; KIP2 antibody; p57 antibody; p57 Kip 2 antibody; p57KIP2 antibody; WBS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49918
Immunogen : Recombinant Human Cyclin-dependent kinase inhibitor 1C protein (221-310AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative reg µLator of cell proliferation. May play a role in maintenance of the non-proliferative state thro µghout life.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDKN1C
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDKN1A Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; CDKN1 antibody; Cdkn1a antibody; CDN1A_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1A antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1A (P21) antibody; Cyclin-dependent kinase inhibitor 1A (p21 Cip1) antibody; DNA Synthesis Inhibitor antibody; MDA-6 antibody; MDA6 antibody; Melanoma differentiation-associated protein 6 antibody; Melanoma differentiation-associated protein antibody; p21 antibody; P21 protein antibody; p21CIP1 antibody; p21Cip1/Waf1 antibody; p21WAF antibody; PIC1 antibody; SDI1 antibody; SLC12A9 antibody; WAF1 antibody; Wild type p53 activated fragment 1 (WAF1) antibody; Wild type p53 activated fragment 1 antibody; Wildtype p53-activated fragment 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P38936
Immunogen : Recombinant Human Cyclin-dependent kinase inhibitor 1 protein (2-164AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cell µLar proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDKN1A
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDKL5 Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : Cdkl5 antibody; CDKL5_HUMAN antibody; Cyclin dependent kinase 5 transcript antibody; Cyclin-dependent kinase-like 5 antibody; EIEE2 antibody; ISSX antibody; Serine/threonine kinase 9 antibody; Serine/threonine-protein kinase 9 antibody; Stk9 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O76039
Immunogen : Recombinant Human Cyclin-dependent kinase-like 5 protein (790-921AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Mediates phosphorylation of MECP2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDKL5
Research Areas : Neuroscience; Signal transduction
0.01 € 0.01 EUR
CDKB1 2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDKB1-2 antibody; At2g38620 antibody; T6A23.18Cyclin-dependent kinase B1-2 antibody; CDKB1;2 antibody; EC 2.7.11.22 antibody; EC 2.7.11.23 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Arabidopsis thaliana
UniProt ID : Q2V419
Immunogen : Recombinant Arabidopsis thaliana Cyclin-dependent kinase B1-2 protein (1-311AA)
Raised in : Rabbit
Species Reactivity : Arabidopsis thaliana
Tested Applications :
Background : Together with CDKB1-1 promotes both the last division in the stomatal cell lineage as well as the number of stomata (PubMed : 20675570). In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression thro µghout the stomatal cell lineage (PubMed : 24123248).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDKB1-2
Research Areas : Others
0.01 € 0.01 EUR
CDKAL1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDK5 reg µLatory subunit associated protein 1 like 1 antibody; CDK5 reg µLatory subunit-associated protein 1-like 1 antibody; CDKAL_HUMAN antibody; CDKAL1 antibody; Threonylcarbamoyladenosine tRNA methylthiotransferase antibody; tRNA t 6 A37 methylthiotransferase antibody; tRNA-t(6)A37 methylthiotransferase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5VV42
Immunogen : Recombinant Human Threonylcarbamoyladenosine tRNA methylthiotransferase protein (1-97AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDKAL1
Research Areas : Cell biology
0.01 € 0.01 EUR
CDK7 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 39 kDa protein kinase antibody; CAK antibody; CAK1 antibody; Cdk activating kinase antibody; CDK-activating kinase 1 antibody; CDK-activating kinase antibody; cdk7 antibody; CDK7_HUMAN antibody; CDKN7 antibody; Cell division protein kinase 7 antibody; Cyclin dependent kinase 7 antibody; cyclin-dependent kinase 7 (MO15 homolog; Xenopus laevis; cdk-activating kinase) antibody; Cyclin-dependent kinase 7 antibody; HCAK antibody; Homolog of Xenopus MO15 Cdk activating kinase antibody; Kinase subunit of CAK antibody; MO15 antibody; MO15; Xenopus; homolog of antibody; P39 Mo15 antibody; p39MO15 antibody; Serine threonine kinase Stk1 antibody; Serine/threonine protein kinase 1 antibody; Serine/threonine protein kinase MO15 antibody; STK1 antibody; TFIIH basal transcription factor complex kinase subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P50613
Immunogen : Recombinant Human Cyclin-dependent kinase 7 protein (212-341AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. Cyclin-dependent kinases (CDKs) are activated by the binding to a cyclin and mediate the progression thro µgh the cell cycle. Each different complex controls a specific transition between 2 subsequent phases in the cell cycle. Required for both activation and complex formation of CDK1/cyclin-B during G2-M transition, and for activation of CDK2/cyclins during G1-S transition (but not complex formation). CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. Phosphorylates SPT5/SUPT5H, SF1/NR5A1 POLR2A, p53/TP53, CDK1 CDK2, CDK4, CDK6 and CDK11B/CDK11. CAK activates the cyclin-associated kinases CDK1 CDK2, CDK4 and CDK6 by threonine phosphorylation, thus reg µLating cell cycle progression. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Phosphorylation of POLR2A in complex with DNA promotes transcription initiation by triggering dissociation from DNA. Its expression and activity are constant thro µghout the cell cycle. Upon DNA damage, triggers p53/TP53 activation by phosphorylation, but is inactivated in turn by p53/TP53; this feedback loop may lead to an arrest of the cell cycle and of the transcription, helping in cell recovery, or to apoptosis. Required for DNA-bound peptides-mediated transcription and cell µLar growth inhibition.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK7
Research Areas : Epigenetics and Nuclear Signaling; Cell biology
0.01 € 0.01 EUR
CDK6 Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : CDK 6 antibody; CDK6 antibody; CDK6_HUMAN antibody; Cell division protein kinase 6 antibody; Crk 2 antibody; Crk2 antibody; Cyclin dependent kinase 6 antibody; Cyclin-dependent kinase 6 antibody; MCPH12 antibody; MGC59692 antibody; p40 antibody; PLSTIRE antibody; Serine/threonine protein kinase PLSTIRE antibody; Serine/threonine-protein kinase PLSTIRE antibody; STQTL11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00534
Immunogen : Recombinant Human Cyclin-dependent kinase 6 protein (102-326AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in initiation and maintenance of cell cycle exit during cell differentiation; prevents cell proliferation and reg µLates negatively cell differentiation, but is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventric µLar zone of the lateral ventricles. Required during thymocyte development. Promotes the production of newborn neurons, probably by mod µLating G1 length. Promotes, at least in astrocytes, changes in patterns of gene expression, changes in the actin cytoskeleton including loss of stress fibers, and enhanced motility during cell differentiation. Prevents myeloid differentiation by interfering with RUNX1 and reducing its transcription transactivation activity, but promotes proliferation of normal myeloid progenitors. Delays senescence. Promotes the proliferation of beta-cells in pancreatic islets of Langerhans. May play a role in the centrosome organization during the cell cycle phases (PubMed : 23918663).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK6
Research Areas : Others
0.01 € 0.01 EUR
CDK5RAP3 Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : C53 antibody; CDK5 activator binding protein C53 antibody; CDK5 activator-binding protein C53 antibody; CDK5 reg µLatory subunit associated protein 3 antibody; CDK5 reg µLatory subunit-associated protein 3 antibody; Cdk5rap3 antibody; CK5P3_HUMAN antibody; HSF 27 antibody; HSF27 antibody; IC53 antibody; Ischemic heart CDK5 activator binding protein C53 antibody; LXXLL/leucine zipper containing ARFbinding protein antibody; LZAP antibody; MST016 antibody; OK/SW cl.114 antibody; PP1553 antibody; Protein HSF-27 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96JB5
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 3 protein (42-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation (PubMed : 12054757, PubMed : 12737517). Negatively reg µLates NF-kappa-B-mediated gene transcription thro µgh the control of RELA phosphorylation (PubMed : 17785205, PubMed : 20228063). Also reg µLates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint (PubMed : 15790566, PubMed : 19223857). Thro µgh its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation (PubMed : 16173922). May play a role in the unfolded protein response, mediating the ufmylation of m µLtiple proteins in response to endoplasmic retic µLum stress (PubMed : 23152784). May also play a role in the rupture of the nuclear envelope during apoptosis (PubMed : 23478299). May reg µLate MAPK14 activity by reg µLating its dephosphorylation by PPM1D/WIP1 (PubMed : 21283629).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP3
Research Areas : Cancer; Cell biology; Signal transduction
0.01 € 0.01 EUR
CDK5RAP2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C48 antibody; CDK5 activator-binding protein C48 antibody; CDK5 reg µLatory subunit associated protein 2 antibody; CDK5 reg µLatory subunit-associated protein 2 antibody; CDK5RAP2 antibody; centrosomal protein 215 kDa antibody; Centrosome-associated protein 215 antibody; CEP215 antibody; CK5P2_HUMAN antibody; MCPH3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96SN8
Immunogen : Recombinant Human CDK5 reg µLatory subunit-associated protein 2 protein (996-1111AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Potential reg µLator of CDK5 activity via its interaction with CDK5R1. Negative reg µLator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in reg µLation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional reg µLator of both BUBR1 and MAD2 promoter. Together with MAPRE1 it may promote microtub µLe polymerization, bundle formation, growth and dynamics at the plus ends. Reg µLates centrosomal maturation by recruitment of a gamma-tub µLin ring complex onto centrosomes (PubMed : 26485573).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5RAP2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology; Tags & Cell Markers; Signal transduction
0.01 € 0.01 EUR
CDK5 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdk 5 antibody; Cdk5 antibody; CDK5_HUMAN antibody; Cell division protein kinase 5 antibody; Crk6 antibody; Cyclin dependent kinase 5 antibody; Cyclin-dependent kinase 5 antibody; Protein kinase CDK5 splicing antibody; PSSALRE antibody; Serine threonine protein kinase PSSALRE antibody; Serine/threonine-protein kinase PSSALRE antibody; Tau protein kinase II catalytic subunit antibody; TPKII catalytic subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00535
Immunogen : Recombinant Human Cyclin-dependent-like kinase 5 protein (1-292AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1 MEF2A, SIPA1L1 SH3GLB1 PXN, PAK1 MCAM/MUC18, SEPT5, SYN1 DNM1 AMPH, SYNJ1 CDK16, RAC1 RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1 p53/TP53, HDAC1 APEX1 PTK2/FAK1 huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Reg µLates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins. Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in post-mitotic neurons, and promotes CDK5R1 (p35) expression in an autostim µLation loop. Phosphorylates many downstream substrates such as Rho and Ras family small GTPases (e.g. PAK1 RAC1 RHOA, CDC42) or microtub µLe-binding proteins (e.g. MAPT/TAU, MAP2, MAP1B), and mod µLates actin dynamics to reg µLate neurite growth and/or spine morphogenesis. Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1 and CDK16/PCTAIRE1 as well as endocytosis associated proteins such as DNM1 AMPH and SYNJ1 at synaptic terminals. In the mature central nervous system (CNS), reg µLates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively reg µLating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in response to genotoxic and oxidative stresses enhances its stabilization by preventing ubiquitin ligase-mediated proteasomal degradation, and induces transactivation of p53/TP53 target genes, thus reg µLating apoptosis. Phosphorylation of p35/CDK5R1 enhances its stabilization by preventing calpain-mediated proteolysis producing p25/CDK5R1 and avoiding ubiquitin ligase-mediated proteasomal degradation. During aberrant cell-cycle activity and DNA damage, p25/CDK5 activity elicits cell-cycle activity and double-strand DNA breaks that precedes neuronal death by dereg µLating HDAC1. DNA damage triggered phosphorylation of huntingtin/HTT in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Phosphorylation of PXN reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Negative reg µLator of Wnt/beta-catenin signaling pathway. Activator of the GAIT (IFN-gamma-activated inhibitor of translation) pathway, which suppresses expression of a post-transcriptional reg µLon of proinflammatory genes in myeloid cells; phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase (EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylation of TONEBP/NFAT5 in response to osmotic stress mediates its rapid nuclear localization. MEF2 is inactivated by phosphorylation in nucleus in response to neurotoxin, thus leading to neuronal apoptosis. APEX1 AP-endodeoxyribonuclease is repressed by phosphorylation, res µLting in accum µLation of DNA damage and contributing to neuronal death. NOS3 phosphorylation down reg µLates NOS3-derived nitrite (NO) levels. SRC phosphorylation mediates its ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. May reg µLate endothelial cell migration and angiogenesis via the mod µLation of lamellipodia formation. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. The complex p35/CDK5 participates in the reg µLation of the circadian clock by mod µLating the function of CLOCK protein : phosphorylates CLOCK at \\\'Thr-451\\\' and \\\'Thr-461\\\' and reg µLates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcell µLar distribution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK5
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism
0.01 € 0.01 EUR
CDK4 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdk 4 antibody; cdk4 antibody; CDK4 protein antibody; CDK4_HUMAN antibody; Cell division kinase 4 antibody; Cell division protein kinase 4 antibody; CMM 3 antibody; CMM3 antibody; Crk3 antibody; Cyclin dependent kinase 4 antibody; Cyclin-dependent kinase 4 antibody; Melanoma cutaneous malignant 3 antibody; MGC14458 antibody; p34 cdk4 antibody; PSK J3 antibody; PSK-J3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11802
Immunogen : Recombinant Human Cyclin-dependent kinase 4 protein (2-303AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and reg µLate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression thro µgh the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK4
Research Areas : Isotype/Loading Controls; Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDK3 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdk 3 antibody; Cdk3 antibody; CDK3_HUMAN antibody; CDKN3 antibody; Cell division kinase 3 antibody; Cell division protein kinase 3 antibody; Cyclin dependent kinase 3 antibody; Cyclin-dependent kinase 3 antibody; OTTHUMP00000206828 antibody; p36 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00526
Immunogen : Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1 ATF1 RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1 E2F2 and E2F3 in a RB1-independent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK3
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction
0.01 € 0.01 EUR
CDK2AP2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75956
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP2
Research Areas : Cell biology
0.01 € 0.01 EUR
CDK2AP1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDK2 A1 antibody; CDK2 associated protein 1 antibody; CDK2-associated protein 1 antibody; CDK2AP1 antibody; CDKA1 antibody; CDKA1_HUMAN antibody; Cyclin dependent kinase 2 associated protein 1 antibody; Cyclin-dependent kinase 2-associated protein 1 antibody; Deleted in oral cancer 1 antibody; DOC 1 antibody; DOC 1 related protein antibody; DOC 1R antibody; DOC-1 antibody; DOC1 antibody; DOC1R antibody; DORC1 antibody; p12DOC 1 antibody; Putative oral cancer suppressor antibody; ST19 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14519
Immunogen : Recombinant Human Cyclin-dependent kinase 2-associated protein 1 protein (1-115AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : specific inhibitor of the cell-cycle kinase CDK2
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2AP1
Research Areas : Epigenetics and Nuclear Signaling
0.01 € 0.01 EUR
CDK2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdc2 related protein kinase antibody; cdc2-related protein kinase antibody; CDC28 antibody; CDC2A antibody; Cdk 2 antibody; CDK1 antibody; CDK2 antibody; CDK2_HUMAN antibody; CDKN2 antibody; Cell devision kinase 2 antibody; Cell division protein kinase 2 antibody; Cyclin dependent kinase 2 antibody; cyclin dependent kinase 2-alpha antibody; Cyclin-dependent kinase 2 antibody; kinase Cdc2 antibody; MPF antibody; p33 protein kinase antibody; p33(CDK2) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24941
Immunogen : Recombinant Human Cyclin-dependent kinase 2 protein (1-298AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1 USP37, p53/TP53, NPM1 CDK7, RB1 BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1 B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and mod µLates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. Crucial role in orchestrating a fine balance between cell µLar proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Activity of CDK2 is maximal during S phase and G2; activated by interaction with cyclin E during the early stages of DNA synthesis to permit G1-S transition, and subsequently activated by cyclin A2 (cyclin A1 in germ cells) during the late stages of DNA replication to drive the transition from S phase to mitosis, the G2 phase. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. Phosphorylates CABLES1. Cyclin E/CDK2 prevents oxidative stress-mediated Ras-induced senescence by phosphorylating MYC. Involved in G1-S phase DNA damage checkpoint that prevents cells with damaged DNA from initiating mitosis; reg µLates homologous recombination-dependent repair by phosphorylating BRCA2, this phosphorylation is low in S phase when recombination is active, but increases as cells progress towards mitosis. In response to DNA damage, double-strand break repair by homologous recombination a reduction of CDK2-mediated BRCA2 phosphorylation. Phosphorylation of RB1 disturbs its interaction with E2F1. NPM1 phosphorylation by cyclin E/CDK2 promotes its dissociates from unduplicated centrosomes, thus initiating centrosome duplication. Cyclin E/CDK2-mediated phosphorylation of NPAT at G1-S transition and until prophase stim µLates the NPAT-mediated activation of histone gene transcription during S phase. Required for vitamin D-mediated growth inhibition by being itself inactivated. Involved in the nitric oxide- (NO) mediated signaling in a nitrosylation/activation-dependent manner. USP37 is activated by phosphorylation and thus triggers G1-S transition. CTNNB1 phosphorylation reg µLates ins µLin internalization. Phosphorylates FOXP3 and negatively reg µLates its transcriptional activity and protein stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDK17 Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : 6430598J10Rik antibody; CDK17 antibody; CDK17_HUMAN antibody; Cell division protein kinase 17 antibody; Cyclin-dependent kinase 17 antibody; EC 2.7.1.37 antibody; MGC25109 antibody; PCTAIRE-motif protein kinase 2 antibody; PCTK2 antibody; Protein kinase cdc2-related PCTAIRE-2 antibody; Serine/threonine-protein kinase PCTAIRE-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q00537
Immunogen : Recombinant Human Cyclin-dependent kinase 17 protein (337-523AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May play a role in terminally differentiated neurons. Has a Ser/Thr-phosphorylating activity for histone H1 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK17
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction
0.01 € 0.01 EUR
CDK13 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDC2 related protein kinase 5 antibody; CDC2-related protein kinase 5 antibody; CDC2L antibody; CDK13 antibody; CDK13_HUMAN antibody; cell division controller cholinesterase related antibody; cell division cycle 2 like 5 (cholinesterase related cell division controller) antibody; cell division cycle 2 like 5 antibody; Cell division cycle 2 like protein kinase 5 antibody; Cell division cycle 2-like protein kinase 5 antibody; Cell division protein kinase 13 antibody; CHED antibody; Cholinesterase related cell division controller antibody; Cholinesterase-related cell division controller antibody; cyclin dependent kinase 13 antibody; Cyclin-dependent kinase 13 antibody; hCDK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14004
Immunogen : Recombinant Human Cyclin-dependent kinase 13 protein (1-170AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1 thereby acting as a key reg µLator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at \'Lys-50\' and \'Lys-51\', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK13
Research Areas : Epigenetics and Nuclear Signaling; Cell biology
0.01 € 0.01 EUR
CDK12 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : arginine/serine-rich antibody; Cdc2 related kinase arginine/serine rich antibody; CDC2 related protein kinase 7 antibody; Cdc2-related kinase antibody; CDC2-related protein kinase 7 antibody; Cdk12 antibody; CDK12_HUMAN antibody; Cell division cycle 2 related protein kinase 7 antibody; Cell division cycle 2-related protein kinase 7 antibody; Cell division protein kinase 12 antibody; CRK7 antibody; CRKR antibody; CrkRS antibody; Cyclin-dependent kinase 12 antibody; EC 2.7.11.22 antibody; hCDK12 antibody; kiaa0904 antibody; Pksc antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NYV4
Immunogen : Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key reg µLator of transcription elongation. Reg µLates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates \'Ser-5\' in CTD repeats that are already phosphorylated at \'Ser-7\', but can also phosphorylate \'Ser-2\'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in reg µLation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK12
Research Areas : Cancer; Signal transduction
0.01 € 0.01 EUR
CDK11A Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CD11A_HUMAN antibody; CDC2L2 antibody; CDC2L3 antibody; CDK11 antibody; CDK11 p110 antibody; CDK11 p46 antibody; CDK11 p58 antibody; CDK11A antibody; Cell division cycle 2 like 2 (PITSLRE proteins) antibody; Cell division cycle 2-like protein kinase 2 antibody; Cell division protein kinase 11A antibody; Cyclin-dependent kinase 11A antibody; Galactosyltransferase-associated protein kinase p58/GTA antibody; p58GTA antibody; PITSLRE antibody; PITSLRE B antibody; PITSLRE protein kinase beta antibody; PITSLRE serine/threonine-protein kinase CDC2L2 antibody; PITSLREB antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQ88
Immunogen : Recombinant Human Cyclin-dependent kinase 11A protein (5-216AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK11A
Research Areas : Epigenetics and Nuclear Signaling
0.01 € 0.01 EUR
CDK1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdc 2 antibody; Cdc2 antibody; CDC28A antibody; CDK 1 antibody; CDK1 antibody; CDK1_HUMAN antibody; CDKN1 antibody; CELL CYCLE CONTROLLER CDC2 antibody; Cell division control protein 2 antibody; Cell division control protein 2 homolog antibody; Cell division cycle 2 G1 to S and G2 to M antibody; Cell division protein kinase 1 antibody; Cell Divsion Cycle 2 Protein antibody; Cyclin Dependent Kinase 1 antibody; Cyclin-dependent kinase 1 antibody; DKFZp686L20222 antibody; MGC111195 antibody; p34 Cdk1 antibody; p34 protein kinase antibody; P34CDC2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06493
Immunogen : Recombinant Human Cyclin-dependent kinase 1 protein (9-101AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a key role in the control of the eukaryotic cell cycle by mod µLating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and reg µLates G1 progress and G1-S transition via association with m µLtiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1 Bcl-xL/BCL2L1 BRCA2, CALD1 CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1 CDK7, CEBPB, CHAMP1 DMD/dystrophin, EEF1 proteins/EF-1 EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1 UBE2A/hHR6A, HIST1H1 proteins/histone H1 HMGA1 HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1 MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1 MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1 NCL, NUCKS1 NPM1/numatrin, ORC1 PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1 µL40/R2, RAB4A, RAP1GAP, RCC1 RPS6KB1/S6K1 KHDRBS1/SAM68, ESPL1 SKI, BIRC5/survivin, STIP1 TEX14, beta-tub µLins, MAPT/TAU, NEDD1 VIM/vimentin, TK1 FOXO1 RUNX1/AML1 SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair. Reactivated after successf µL DNA repair thro µgh WIP1-dependent signaling leading to CDC25A/B/C-mediated dephosphorylation and restoring cell cycle progression. In proliferating cells, CDK1-mediated FOXO1 phosphorylation at the G2-M phase represses FOXO1 interaction with 14-3-3 proteins and thereby promotes FOXO1 nuclear accum µLation and transcription factor activity, leading to cell death of postmitotic neurons. The phosphorylation of beta-tub µLins reg µLates microtub µLe dynamics during mitosis. NEDD1 phosphorylation promotes PLK1-mediated NEDD1 phosphorylation and subsequent targeting of the gamma-tub µLin ring complex (gTuRC) to the centrosome, an important step for spindle formation. In addition, CC2D1A phosphorylation reg µLates CC2D1A spindle pole localization and association with SCC1/RAD21 and centriole cohesion during mitosis. The phosphorylation of Bcl-xL/BCL2L1 after prolongated G2 arrest upon DNA damage triggers apoptosis. In contrast, CASP8 phosphorylation during mitosis prevents its activation by proteolysis and subsequent apoptosis. This phosphorylation occurs in cancer cell lines, as well as in primary breast tissues and lymphocytes. EZH2 phosphorylation promotes H3K27me3 maintenance and epigenetic gene silencing. CALD1 phosphorylation promotes Schwann cell migration during peripheral nerve regeneration. CDK1-cyclin-B complex phosphorylates NCKAP5L and mediates its dissociation from centrosomes during mitosis (PubMed : 26549230).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDK1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction
0.01 € 0.01 EUR
CDH9 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CADH9_HUMAN antibody; Cadherin 9 type 2 antibody; Cadherin-9 antibody; Cadherin9 antibody; CDH 9 antibody; CDH9 antibody; T1 cadherin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLB4
Immunogen : Recombinant Human Cadherin-9 protein (131-314AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH9
Research Areas : Neuroscience; Signal transduction
0.01 € 0.01 EUR
CDH8 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CADH8_HUMAN antibody; Cadherin 8; type 2 antibody; Cadherin-8 antibody; CDH 8 antibody; Cdh8 antibody; Nbla04261 antibody; Putative protein product of Nbla04261 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55286
Immunogen : Recombinant Human Cadherin-8 protein (653-782AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH8
Research Areas : Others
0.01 € 0.01 EUR
CDH7 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDH7 antibody; CDH7L1Cadherin-7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLB5
Immunogen : Recombinant Human Cadherin-7 protein (146-296AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH7
Research Areas : Signal transduction
0.01 € 0.01 EUR
CDH5 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : 7B 4 antibody; 7B4 antibody; 7B4 antigen antibody; CADH5_HUMAN antibody; Cadherin 5 antibody; Cadherin 5 type 2 antibody; Cadherin 5, type 2 (vasc µLar endothelium) antibody; Cadherin 5, type 2, VE cadherin (vasc µLar epithelium) antibody; cadherin, vasc µLar endothelial antibody; cadherin, vasc µLar endothelial, 1 antibody; Cadherin-5 antibody; Cadherin5 antibody; CD 144 antibody; CD144 antibody; CD144 antigen antibody; CDH 5 antibody; CDH5 antibody; CDH5 protein antibody; Endothelial specific cadherin antibody; FLJ17376 antibody; OTTHUMP00000174777 antibody; Vasc µLar endothelial cadherin antibody; Vasc µLar epithelium cadherin antibody; VE Cad antibody; VE-cadherin antibody; VEC antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P33151
Immunogen : Recombinant Human Cadherin-5 protein (349-569AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology thro µgh control of the cohesion and organization of the intercell µLar junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vasc µLar lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH5
Research Areas : Cancer; Cardiovasc µLar; Signal transduction
0.01 € 0.01 EUR
CDH3 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CADH3_HUMAN antibody; Cadherin 3 antibody; Cadherin 3 precursor antibody; Cadherin 3 type 1 antibody; Cadherin-3 antibody; Cadp antibody; Calcium dependent adhesion protein placental antibody; CDH 3 antibody; CDH3 antibody; CDH3 protein antibody; CDHP antibody; HJMD antibody; P cadherin (placental) antibody; P-cadherin antibody; PCAD antibody; Placental cadherin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P22223
Immunogen : Recombinant Human Cadherin-3 protein (117-360AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH3
Research Areas : Neuroscience; Signal transduction
0.01 € 0.01 EUR
CDH26 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CAD26_HUMAN antibody; Cadherin 26 antibody; Cadherin like 26 antibody; Cadherin-like protein 26 antibody; Cadherin-like protein VR20 antibody; Cdh26 antibody; RP4-551D2.3 antibody; VR20 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IXH8
Immunogen : Recombinant Human Cadherin-like protein 26 protein (1-124AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH26
Research Areas : Signal transduction
0.01 € 0.01 EUR
CDH2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CADH2_HUMAN antibody; Cadherin 2 antibody; Cadherin 2 N cadherin neuronal antibody; Cadherin 2 type 1 antibody; Cadherin 2 type 1 N cadherin neuronal antibody; Cadherin 2; type 1; N-cadherin (neuronal) antibody; Cadherin-2 antibody; Cadherin2 antibody; Calcium dependent adhesion protein neuronal antibody; CD325 antibody; CD325 antigen antibody; CDH2 antibody; CDHN antibody; CDw325 antibody; CDw325 antigen antibody; N cadherin 1 antibody; N-cadherin antibody; NCAD antibody; Neural cadherin antibody; OTTHUMP00000066304 antibody; OTTHUMP00000067378 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P19022
Immunogen : Recombinant Human Cadherin-2 protein (746-906AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a reg µLator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the ad µLt subependymal zone : upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to mod µLate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may reg µLate dendritic spine density (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH2
Research Areas : Cancer; Signal transduction; Stem cells
0.01 € 0.01 EUR
CDH18 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDH18 antibody; CDH14Cadherin-18 antibody; Cadherin-14 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13634
Immunogen : Recombinant Human Cadherin-18 protein (66-251AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH18
Research Areas : Neuroscience; Signal transduction
0.01 € 0.01 EUR
CDH15 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CAD15_HUMAN antibody; Cadherin 14 antibody; Cadherin 15 antibody; Cadherin 15, type 1 M cadherin (myotub µLe) antibody; Cadherin 3 antibody; Cadherin-14 antibody; Cadherin-15 antibody; Cadherin14 antibody; Cadherin15 antibody; Cadherin3 antibody; CCAD antibody; CDH 14 antibody; CDH 15 antibody; CDH 3 antibody; CDH14 antibody; Cdh15 antibody; CDH3 antibody; CDHM antibody; M-cadherin antibody; MCAD antibody; MRD3 antibody; Muscle cadherin antibody; Myotub µLe cadherin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55291
Immunogen : Recombinant Human Cadherin-15 protein (639-766AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH15
Research Areas : Neuroscience; Cell biology; Signal transduction
0.01 € 0.01 EUR
CDH12 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Br cadherin antibody; BR-cadherin antibody; Brain cadherin antibody; CAD12_HUMAN antibody; cadherin 12 (N cadherin 2) antibody; Cadherin 12 antibody; Cadherin 12 precursor antibody; Cadherin 12 type 2 (N cadherin 2) antibody; Cadherin 12 type 2 antibody; Cadherin neural type 2 antibody; Cadherin-12 antibody; CDH12 antibody; CDHB antibody; FLJ34857 antibody; N cadherin 2 antibody; N-cadherin 2 antibody; Neural type cadherin 2 antibody; Neuronal cadherin 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55289
Immunogen : Recombinant Human Cadherin-12 protein (56-605AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH12
Research Areas : Signal transduction
0.01 € 0.01 EUR
CDH11 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CAD11 antibody; CAD11_HUMAN antibody; Cadherin 11 antibody; Cadherin 11 type 2 antibody; Cadherin 11 type 2 OB cadherin (osteoblast) antibody; Cadherin-11 antibody; Cdh11 antibody; CDHOB antibody; OB antibody; OB-cadherin antibody; OBcadherin antibody; OSF-4 antibody; OSF4 antibody; Osteoblast cadherin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P55287
Immunogen : Recombinant Human Cadherin-11 protein (637-796AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH11
Research Areas : Cancer; Signal transduction
0.01 € 0.01 EUR
CDH1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Arc 1 antibody; CADH1_HUMAN antibody; Cadherin 1 antibody; cadherin 1 type 1 E-cadherin antibody; Cadherin-1 antibody; Cadherin1 antibody; CAM 120/80 antibody; CD 324 antibody; CD324 antibody; CD324 antigen antibody; cdh1 antibody; CDHE antibody; E-Cad/CTF3 antibody; E-cadherin antibody; ECAD antibody; Epithelial cadherin antibody; epithelial calcium dependant adhesion protein antibody; LCAM antibody; Liver cell adhesion molec µLe antibody; UVO antibody; Uvomor µLin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P12830
Immunogen : Recombinant Human Cadherin-1 protein (23-621AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cadherins are calcium-dependent cell adhesion proteins (PubMed : 11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms reg µLating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed : 11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH1
Research Areas : Cancer; Developmental biology; Signal transduction
0.01 € 0.01 EUR
CDH 1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDH-1; antibody; CDH-2Cellobiose dehydrogenase antibody; CDH antibody; EC 1.1.99.18 antibody; Cellobiose-quinone oxidoreductase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Phanerochaete chrysosporium (White-rot fungus) (Sporotrichum pruinosum)
UniProt ID : Q01738
Immunogen : Recombinant Phanerochaete chrysosporium Cellobiose dehydrogenase protein (19-208AA)
Raised in : Rabbit
Species Reactivity : Phanerochaete chrysosporium
Tested Applications :
Background : Degrades both lignin and cell µLose. Oxidizes cellobiose to cellobionolactone.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDH-1
Research Areas : Others
0.01 € 0.01 EUR
CDCA7L Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : c Myc Interacting protein JPO2 antibody; CDA7L_HUMAN antibody; Cdca7l antibody; Cell division cycle-associated 7-like protein antibody; DKFZp762L0311 antibody; HR1 antibody; JPO2 antibody; Protein JPO2 antibody; R1 antibody; RAM2 antibody; Transcription factor RAM2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96GN5
Immunogen : Recombinant Human Cell division cycle-associated 7-like protein (14-167AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in transcriptional reg µLation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the f µLl transforming effect of MYC in med µLloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDCA7L
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDC73 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C1orf28 antibody; CDC 73 antibody; Cdc73 antibody; CDC73_HUMAN antibody; Cell division cycle 73 antibody; Cell division cycle 73 Paf1/RNA polymerase II complex component homolog antibody; Cell division cycle 73 Paf1/RNA polymerase II complex component like protein antibody; Cell division cycle protein 73 homolog antibody; FIHP antibody; FLJ23316 antibody; HPT JT antibody; HPTJT antibody; HRPT 2 antibody; HRPT1 antibody; HRPT2 antibody; Hyperparathyroidism 2 (with jaw tumor) antibody; Hyperparathyroidism 2 antibody; Hyperparathyroidism 2 protein antibody; HYX antibody; Paf1/RNA polymerase II complex component antibody; Parafibromin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6P1J9
Immunogen : Recombinant Human Parafibromin protein (74-346AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression thro µgh the reg µLation of cyclin D1/PRAD1 expression. Component of the PAF1 complex (PAF1C) which has m µLtiple functions during transcription by RNA polymerase II and is implicated in reg µLation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II thro µgh interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stim µLates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis thro µgh association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably thro µgh association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby reg µLating gene transcription. Connects PAF1C with the cleavage and polyadenylation specificity factor (CPSF) complex and the cleavage stim µLation factor (CSTF) complex, and with Wnt signaling. Involved in polyadenylation of mRNA precursors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC73
Research Areas : Epigenetics and Nuclear Signaling; Cancer
0.01 € 0.01 EUR
CDC6 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdc 18L antibody; Cdc 6 antibody; CDC18 (cell division cycle 18; S.pombe; homolog) like antibody; CDC18 (S.pombe) antibody; Cdc18 related protein antibody; CDC18(S.pombe) antibody; Cdc18-related protein antibody; Cdc18L antibody; cdc6 antibody; CDC6 cell division cycle 6 homolog antibody; CDC6 related protein antibody; CDC6-related protein antibody; CDC6_HUMAN antibody; Cdc6p antibody; CELL CYCLE CONTROLLER CDC6 antibody; Cell division control protein 6 antibody; Cell division control protein 6 homolog antibody; Cell division cycle 6 homolog (S. cerevisiae) antibody; Cell division cycle 6 homolog antibody; Cell division cycle 6; S. cerevisiae; homolog of antibody; HsCDC 6 antibody; HsCDC18 antibody; HsCDC6 antibody; p62 antibody; p62(cdc 6) antibody; p62(cdc6) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99741
Immunogen : Recombinant Human Cell division control protein 6 homolog protein (1-141AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC6
Research Areas : Epigenetics and Nuclear Signaling; Cell biology
0.01 € 0.01 EUR
CDC42EP3 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDC42EP3 antibody; BORG2 antibody; CEP3Cdc42 effector protein 3 antibody; Binder of Rho GTPases 2 antibody; MSE55-related Cdc42-binding protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UKI2
Immunogen : Recombinant Human Cdc42 effector protein 3 protein (1-226AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC42EP3
Research Areas : Signal transduction
0.01 € 0.01 EUR
CDC42EP2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Binder of Rho GTPases 1 antibody; BORG1 antibody; BORG1_HUMAN antibody; CDC42 effector protein (Rho GTPase binding) 2 antibody; Cdc42 effector protein 2 antibody; Cdc42ep2 antibody; CEP2 antibody; CRIB-containing BOGR1 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14613
Immunogen : Recombinant Human Cdc42 effector protein 2 protein (9-210AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC42EP2
Research Areas : Signal transduction
0.01 € 0.01 EUR
CDC42BPB Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDC42 binding protein kinase beta antibody; CDC42-binding protein kinase beta antibody; CDC42BPB antibody; DMPK like beta antibody; DMPK-like beta antibody; KIAA1124 antibody; MRCK beta antibody; MRCKB_HUMAN antibody; Myotonic dystrophy kinase related CDC42 binding kinase beta antibody; Myotonic dystrophy kinase-related CDC42-binding kinase beta antibody; Myotonic dystrophy protein kinase like beta antibody; Myotonic dystrophy protein kinase-like beta antibody; Serine/threonine protein kinase MRCK beta antibody; Serine/threonine-protein kinase MRCK beta antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y5S2
Immunogen : Recombinant Human Serine/threonine-protein kinase MRCK beta protein (1609-1711AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the reg µLation of cytoskeleton reorganization and cell migration. Reg µLates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1 is involved in mod µLating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC42BPB
Research Areas : Signal transduction
0.01 € 0.01 EUR
CDC42 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDC42 antibody; CDC42_HUMAN antibody; CDC42Hs antibody; Cell division control protein 42 homolog antibody; Cell division cycle 42 (GTP binding protein 25kDa) antibody; Cell division cycle 42 antibody; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein; 25kD)) antibody; dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein; 25kD)) antibody; G25K antibody; G25K GTP-binding protein antibody; Growth reg µLating protein antibody; GTP binding protein 25kDa antibody; Small GTP binding protein CDC42 antibody; TKS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P60953
Immunogen : Recombinant Human Cell division control protein 42 homolog protein (2-188AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to reg µLate cell µLar responses. Involved in epithelial cell polarization processes. Reg µLates the bipolar attachment of spindle microtub µLes to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC42
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction
0.01 € 0.01 EUR
CDC37 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDC 37 antibody; Cdc37 antibody; CDC37 cell division cycle 37 homolog antibody; CDC37 cell division cycle 37 S cerevisiae homolog antibody; CDC37 cell division cycle 37; S cerevisiae; homolog of antibody; Cdc37 homolog antibody; CDC37 protein antibody; CDC37_HUMAN antibody; CDC37A antibody; cell division cycle 37 antibody; Cell division cycle 37 homolog antibody; Hsp90 chaperone protein kinase targeting subunit antibody; Hsp90 chaperone protein kinase targeting subunit p50Cdc37 antibody; Hsp90 chaperone protein kinase-targeting subunit antibody; Hsp90 co chaperone Cdc37 antibody; Hsp90 co-chaperone Cdc37 antibody; p50 antibody; p50Cdc37 antibody; S cerevisiae hypothetical protein CDC37 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16543
Immunogen : Recombinant Human Hsp90 co-chaperone Cdc37 protein (89-175AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, res µLting in stabilization and promotion of their activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC37
Research Areas : Epigenetics and Nuclear Signaling; Cell biology
0.01 € 0.01 EUR
CDC34 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdc 34 antibody; Cdc34 antibody; Cell division cycle 34 antibody; Cell division cycle 34 homolog (S. cerevisiae) antibody; Cell division cycle 34 homolog antibody; E2 CDC34 antibody; UB2R1_HUMAN antibody; UBC 3 antibody; UBC3 antibody; UBCH3 antibody; UBE2 R1 antibody; UBE2R1 antibody; Ubiquitin carrier protein antibody; Ubiquitin conj µgating enzyme Cdc34 antibody; Ubiquitin conj µgating enzyme E2 32 kDa complementing antibody; Ubiquitin protein ligase antibody; Ubiquitin protein ligase R1 antibody; Ubiquitin-conj µgating enzyme E2 R1 antibody; Ubiquitin-conj µgating enzyme E2-32 kDa complementing antibody; Ubiquitin-conj µgating enzyme E2-CDC34 antibody; Ubiquitin-protein ligase R1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49427
Immunogen : Recombinant Human Ubiquitin-conj µgating enzyme E2 R1 protein (1-236AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes \'Lys-48\'-linked polyubiquitination. Cooperates with the E2 UBCH5C and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions \'Lys-21\' and/or \'Lys-22\' with a monoubiquitin. Cooperates with the SCF(SKP2) E3 ligase complex to reg µLate cell proliferation thro µgh ubiquitination and degradation of MYBL2 and KIP1. Involved in ubiquitin conj µgation and degradation of CREM isoform ICERIIgamma and ATF15 res µLting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles. Involved in the reg µLation of the cell cycle G2/M phase thro µgh its targeting of the WEE1 kinase for ubiquitination and degradation. Also involved in the degradation of beta-catenin. Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC34
Research Areas : Epigenetics and Nuclear Signaling
0.01 € 0.01 EUR
CDC27 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : ANAPC3 antibody; Anaphase Promoting Complex 3 antibody; Anaphase promoting complex protein 3 antibody; Anaphase Promoting Complex Subunit 3 antibody; Anaphase-promoting complex subunit 3 antibody; APC 3 antibody; APC3 antibody; Cdc 27 antibody; Cdc27 antibody; CDC27 homolog antibody; CDC27_HUMAN antibody; CDC27Hs antibody; Cell Division Cycle 27 antibody; Cell division cycle protein 27 homolog antibody; D0S1430E antibody; D17S978E antibody; H NUC antibody; H-NUC antibody; HNUC antibody; Nuc2 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30260
Immunogen : Recombinant Human Cell division cycle protein 27 homolog protein (258-431AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-reg µLated E3 ubiquitin ligase that controls progression thro µgh mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins : it mainly mediates the formation of \'Lys-11\'-linked polyubiquitin chains and, to a lower extent, the formation of \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC27
Research Areas : Cell biology
0.01 € 0.01 EUR
CDC26 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDC26 antibody; ANAPC12 antibody; C9orf17Anaphase-promoting complex subunit CDC26 antibody; Anaphase-promoting complex subunit 12 antibody; APC12 antibody; Cell division cycle protein 26 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NHZ8
Immunogen : Recombinant Human Anaphase-promoting complex subunit CDC26 protein (1-85AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-reg µLated E3 ubiquitin ligase that controls progression thro µgh mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins : it mainly mediates the formation of \'Lys-11\'-linked polyubiquitin chains and, to a lower extent, the formation of \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conj µgating enzymes to the complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC26
Research Areas : Cell biology
0.01 € 0.01 EUR
CDC25C Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CDC 25 antibody; Cdc 25C antibody; CDC25 antibody; CDC25C antibody; Cell division cycle 25 homolog C antibody; Cell division cycle 25C antibody; Cell division cycle 25C protein antibody; Dual specificity phosphatase Cdc25C antibody; M phase inducer phosphatase 3 antibody; M-phase inducer phosphatase 3 antibody; Mitosis inducer CDC25 antibody; MPIP3 antibody; MPIP3_HUMAN antibody; Phosphotyrosine phosphatase antibody; PPP1R60 antibody; protein phosphatase 1 reg µLatory subunit 60 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30307
Immunogen : Recombinant Human M-phase inducer phosphatase 3 protein (1-473AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC25C
Research Areas : Epigenetics and Nuclear Signaling; Cell biology
0.01 € 0.01 EUR
CDC25B Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : AI604853 antibody; Cdc 25B antibody; Cdc25b antibody; CDC25HU2 antibody; Cdc25m2 antibody; Cell division cycle 25 homolog B antibody; Cell division cycle 25B antibody; Cell division cycle 25B isoform 1 antibody; Cell division cycle 25B isoform 2 antibody; Cell division cycle 25B isoform 3 antibody; Cell division cycle 25B isoform 4 antibody; Cell division cycle 25B isoform 5 antibody; Dual specificity phosphatase Cdc25B antibody; EC 3.1.3.48 antibody; M phase inducer phosphatase 2 antibody; M-phase inducer phosphatase 2 antibody; MPIP2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30305
Immunogen : Recombinant Human M-phase inducer phosphatase 2 protein (1-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stim µLates its kinase activity. The three isoforms seem to have a different level of activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC25B
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDC25A Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Cdc 25a antibody; CDC25A antibody; CDC25A2 antibody; CDC25A2 CAG isoform antibody; Cell division cycle 25 homolog A (S. pombe) antibody; Cell division cycle 25A antibody; Cell division cycle 25A isoform a antibody; Cell division cycle 25A isoform b antibody; D9Ertd393e antibody; Dual specificity phosphatase Cdc25A antibody; M phase inducer phosphatase 1 antibody; M-phase inducer phosphatase 1 antibody; MGC115549 antibody; MPIP1_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30304
Immunogen : Recombinant Human M-phase inducer phosphatase 1 protein (70-337AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stim µLates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC25A
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 € 0.01 EUR
CDC23 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : ANAPC8 antibody; Anaphase promoting complex subunit 8 antibody; Anaphase-promoting complex subunit 8 antibody; Apc 8 antibody; APC8 antibody; Cdc 23 antibody; CDC23 antibody; CDC23_HUMAN antibody; cell division cycle 23 antibody; Cell division cycle 23 homolog antibody; Cell division cycle protein 23 antibody; Cell division cycle protein 23 homolog antibody; Cut23 antibody; Cyclosome subunit 8 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UJX2
Immunogen : Recombinant Human Cell division cycle protein 23 homolog protein (62-142AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-reg µLated E3 ubiquitin ligase that controls progression thro µgh mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins : it mainly mediates the formation of \'Lys-11\'-linked polyubiquitin chains and, to a lower extent, the formation of \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CDC23
Research Areas : Cancer; Cell biology
0.01 € 0.01 EUR