RSK3 (Phospho Thr353) rabbit pAb - 100 μL

Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Cofactor: Magnesium. enzyme regulation: Activated by multiple phosphorylations on threonine and serine residues. function: Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. PTM: Autophosphorylated on Ser-377, as part of the activation process. similarity: Belongs to the protein kinase superfamily. similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. similarity: Contains 1 AGC-kinase C-terminal domain. similarity: Contains 2 protein kinase domains. subunit: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation. tissue specificity: Expressed in many tissues. Highest expression in lung and skeletal muscle.