U-PAR rabbit pAb - 50 μL

Function: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. similarity: Contains 3 UPAR/Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.