ZIS rabbit pAb - 100 μL

Domain: The RanBP2-type zinc fingers mediate binding to RNA. function: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection. PTM: Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR. sequence Caution: Intron retention. similarity: Belongs to the ZRANB2 family. similarity: Contains 2 RanBP2-type zinc fingers. subunit: Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.