Volume : 50 µg
Clone Number :
Aliases : Alkaline phosphodiesterase 1 antibody; ARHR2 antibody; COLED antibody; E-NPP 1 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 antibody; ENPP1 antibody; ENPP1_HUMAN antibody; Ly 41 antigen antibody; M6S1 antibody; Membrane component chromosome 6 surface marker 1 antibody; NPP1 antibody; NPPase antibody; NPPS antibody; Nucleotide pyrophosphatase antibody; PC 1 antibody; PC-1 antibody; PCA1 antibody; PDNP1 antibody; Phosphodiesterase I/nucleotide pyrophosphatase 1 antibody; Plasma cell membrane glycoprotein 1 antibody; Plasma-cell membrane glycoprotein PC-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P22413
Immunogen : Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 protein (1-75AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : By generating PPi, plays a role in reg µLating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5\' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3\',5\'-cAMP to AMP. May also be involved in the reg µLation of the availability of nucleotide s µgars in the endoplasmic retic µLum and Golgi, and the reg µLation of purinergic signaling. Appears to mod µLate ins µLin sensitivity and function.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ENPP1
Research Areas : Cell biology; Metabolism; Signal transduction